Evidence map›Paper›PMID 34279379›Full record

ArticleMolecules (Basel, Switzerland)2021

Optimization of an Extraction Process to Obtain a Food-Grade Sulforaphane-Rich Extract from Broccoli (

Francis González, Julián Quintero, Rodrigo Del Río, Andrea Mahn

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06561893 (Effect of L. Plantarum Probiotic Supplementation on Broccoli Sulforaphane Bioavailability), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06561893 nacompletednot on this mapstarted 2024, after this paper: background citation

Effect of L. Plantarum Probiotic Supplementation on Broccoli Sulforaphane Bioavailability: Randomised Double-blind Placebo-controlled Crossover Study

TypeinterventionalSponsorUniversity of ExeterRan2024 to 2025Enrolled13ConditionsNutrition, HealthyArmsBroccoli sprouts extract supplementation
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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  11. The Anti-Inflammatory Effects of Broccoli (Current issues in molecular biology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Francis GonzálezDepartamento de Ingeniería Química, Facultad de Ingeniería, Universidad de Santiago de Chile (USACH), Santiago 9160000, Chile.ORCID 0000-0001-6478-4463
Julián QuinteroDepartamento de Ingeniería Química, Facultad de Ingeniería, Universidad de Santiago de Chile (USACH), Santiago 9160000, Chile.ORCID 0000-0003-1224-5649
Rodrigo Del RíoLaboratory of Cardiorespiratory Control, Departamento de Fisiología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile (PUC), Santiago 3542000, Chile.ORCID 0000-0002-2562-806X
Andrea MahnDepartamento de Ingeniería Química, Facultad de Ingeniería, Universidad de Santiago de Chile (USACH), Santiago 9160000, Chile.ORCID 0000-0001-6082-0279
Universidad de Santiago de Chile · CLPontificia Universidad Católica de Chile · CL

Funding

Center of Applied Ecology and Sustainability CONICYT/PIA/BASAL FB 0002Fondo Nacional de Investigación Científica y Tecnológica FONDECYT 1180172Fundación para la Innovación Agraria PYT-2018-0316Vicerrectoría de Investigación, Desarrollo e Innovación, USACH DICYT 081711MO
6 · The paper itself

Abstract

Sulforaphane (SFN) is a powerful health-promoting compound found in broccoli in the form of its inactive precursor, glucoraphanin (GFN). SFN formation occurs through the enzymatic hydrolysis of glucoraphanin by myrosinase under specific chemical conditions. Its incorporation in food formulations has been hindered by the thermal instability of SFN and low concentration in

Indexed as

BrassicaChemical FractionationEthanolGlucosinolatesIsothiocyanatesOximesPlant ExtractsSulfoxidesEthanolglucoraphaninGlucosinolatesIsothiocyanatesOximesPlant ExtractssulforaphaneSulfoxidesbroccoliethanol extractionoptimizationsulforaphane

Identifiers

PMID34279379
PMCPMC8272218
OpenAlexW3175615978

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.