Evidence map›Paper›PMID 34279089›Full record

ArticleBiochemistry2021

Variable Autoinhibition among Deafness-Associated Variants of Diaphanous 1 (DIAPH1).

Rabina Lakha, Angela M Montero, Tayyaba Jabeen, Christina C Costeas, Jia Ma, Christina L Vizcarra

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rabina LakhaDepartment of Chemistry, Barnard College, New York, New York 10027, United States.
Angela M MonteroDepartment of Chemistry, Barnard College, New York, New York 10027, United States.
Tayyaba JabeenDepartment of Chemistry, Barnard College, New York, New York 10027, United States.
Christina C CosteasDepartment of Chemistry, Barnard College, New York, New York 10027, United States.
Jia MaDepartment of Chemistry, Columbia University, New York, New York 10027, United States.
Christina L VizcarraDepartment of Chemistry, Barnard College, New York, New York 10027, United States.ORCID 0000-0003-0564-9776
Barnard College · USColumbia University · US

Funding

Molecular mechanisms underlying formin-associated inherited deafnessR15DC016462 · NIDCD · BARNARD COLLEGE · PI VIZCARRA, CHRISTINA LUISA · 2018 to 2018
$425k
Combination CD-Fluorescence Polarization Spectrophotometer for the Columbia Precision Biomolecular Characterization FacilityS10OD025102 · OD · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI HUNT, JOHN FRANCIS · 2018 to 2018
$138k
NIDCD NIH HHS R15 DC016462NIH HHS S10 OD025102
6 · The paper itself

Abstract

One of the earliest mapped human deafness genes,

Indexed as

MutationActinsCell LineForminsHearing LossHumansModels, MolecularProtein FoldingProtein StabilityActinsDIAPH1 protein, humanFormins

Identifiers

PMID34279089
PMCPMC8447886
OpenAlexW3183963511

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.