Evidence map›Paper›PMID 34278468›Full record

ArticleMolecular medicine reports2021

Psoralen inhibits the inflammatory response and mucus production in allergic rhinitis by inhibiting the activator protein 1 pathway and the downstream expression of cystatin‑SN.

Wenying Gao, Zhenglong Jin, Yanxia Zheng, Youjia Xu

Open access · hybridAbstract read
In one paragraph

Article in Molecular medicine reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Psoralen Isolated from the Roots ofMediators of inflammation · 2024
    Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Wenying GaoGuangzhou University of Chinese Medicine, Guangzhou, Guangdong 510000, P.R. China.
Zhenglong JinDepartment of Neurology, Jiangmen Wuyi Hospital of TCM Affiliated Jiangmen TCM Hospital of Ji'nan University, Jiangmen, Guangdong 529000, P.R. China.
Yanxia ZhengDepartment of TCM Pediatrics, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, Guangdong 510000, P.R. China.
Youjia XuDepartment of TCM Pediatrics, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou, Guangdong 510000, P.R. China.
Guangdong Provincial Hospital of Traditional Chinese Medicine · CNGuangzhou University of Chinese Medicine · CNJiangmen Wuyi Traditional Chinese Medicine Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psoralen (PSO) exerts anti‑inflammatory pharmacological effects and plays an important role in a variety of inflammatory diseases. However, the effects of PSO with allergic rhinitis (AR) are yet to be reported. In the present study, an

Indexed as

Cell LineChemokine CCL11CytokinesEpithelial CellsFicusinGranulocyte-Macrophage Colony-Stimulating FactorHumansInflammationInterleukin-13Mucin 5ACMucusNasal MucosaReactive Oxygen SpeciesRhinitis, AllergicSalivary CystatinsTranscription Factor AP-1CCL11 protein, humanChemokine CCL11CytokinesFicusinGranulocyte-Macrophage Colony-Stimulating FactorInterleukin-13Mucin 5ACReactive Oxygen SpeciesSalivary CystatinsTranscription Factor AP-1activator protein 1 pathwayallergic rhinitiscystatin‑SNinflammatory responsemucus productionpsoralen

Identifiers

PMID34278468
PMCPMC8299190
OpenAlexW3179242185

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.