ArticleF&S reports2021
Racial differences in anxiety, depression, and quality of life in women with polycystic ovary syndrome.
Article in F&S reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- The lived experiences of women with polycystic ovary syndrome and its psychological challenges: A systematic review and meta-synthesis.Archives of women's mental health · 2026Pooled it
- Depressive and Anxiety Symptoms in Women with Polycystic Ovary Syndrome: A Meta-Analysis.Journal of clinical medicine · 2026Review
- Global and regional burden of polycystic ovary syndrome, 1990-2021: a systematic analysis of the global burden of disease study 2021.BMC women's health · 2025Article
- Influence of mood disorders on outcomes of polycystic ovarian syndrome - A national inpatient sample study - 2016-2020.Comprehensive psychoneuroendocrinology · 2025Article
- Psychological symptoms in perimenarcheal adolescents: association with PCOS risk factors.Frontiers in endocrinology · 2025Article
- Racial Differences in Psychiatric Symptoms, Maladaptive Eating, and Lifestyle Behaviors After Bariatric Surgery.Journal of racial and ethnic health disparities · 2024Article
- Mental Health Across the Menstrual Cycle in Polycystic Ovary Syndrome: Insights and Implications.Current psychiatry reports · 2024Review
- Productivity loss due to polycystic ovary syndrome and its relationship to race, mental health and healthcare delivery indices.F&S reports · 2024Article
- Bridging the Gap: Integrating Awareness of Polycystic Ovary Syndrome Into Mental Health Practice.Focus (American Psychiatric Publishing) · 2024Review
- Article
- Depression in Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2023Review
- Racial and ethnic disparities in polycystic ovary syndrome.Fertility and sterility · 2023Review
- Lifestyle management in polycystic ovary syndrome - beyond diet and physical activity.BMC endocrine disorders · 2023Review
- A Global Survey of Ethnic Indian Women Living with Polycystic Ovary Syndrome: Co-Morbidities, Concerns, Diagnosis Experiences, Quality of Life, and Use of Treatment Methods.International journal of environmental research and public health · 2022Article
- Polycystic ovary syndrome and postpartum depression among Hispanics and non-Hispanics: a population-based study.AJOG global reports · 2022Article
- Anxiety and Depression in Women with Polycystic Ovary Syndrome.Medicina (Kaunas, Lithuania) · 2022Article
- Polycystic ovary syndrome: Criteria, phenotypes, race and ethnicity.Reproductive medicine and biologyReview
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo evaluate racial differences in the anxiety and depression prevalence and scores in women with polycystic ovary syndrome (PCOS).
designCross-sectional.
settingAcademic institution. PATIENTS: Reproductive-aged women with PCOS (n = 272) and controls (n = 295).
interventionsHospital anxiety and depression scale and modified PCOS quality-of-life survey (MPCOS-Q).
main outcome measuresDifferences in depression and anxiety scores and quality-of-life score measured using the hospital anxiety and depression scale and MPCOS-Q were determined between White and Black women with PCOS. Multivariable correlation regressions assessed the association of the Ferriman-Gallwey score, total testosterone, body mass index (BMI), and homeostatic model assessment of insulin resistance with anxiety, depression, and quality-of-life scores.
resultsMultivariable regression controlling for age, BMI, and socioeconomic status showed that White women with PCOS had a significantly higher prevalence of anxiety than Black women with PCOS (75.9% vs. 61.3%) and significantly higher anxiety scores (mean ± SD, 10.3 ± 4.1 vs. 8.7 ± 4.6). The prevalence of depression (24.4% vs. 29%) and depression scores (4.8 ± 3.6 vs. 5.1 ± 4.0) was not significantly different. In multivariable correlation regressions, the interaction between BMI and race in its association with anxiety scores was significant. The association of race with Ferriman-Gallwey score, total testosterone, or homeostatic model assessment of insulin resistance was not significant. In multivariable models, although the total MPCOS-Q scores were similar, the infertility domain was significantly lower in Black women with PCOS (mean ± SD, 12.6 ± 7.8 vs. 17.5 ± 6.8) indicating a lower quality of life related to infertility.
conclusionRacial differences identified in the prevalence of anxiety and MPCOS-Q domains suggest the importance of routine screening and provide an opportunity for targeted interventions based on race.
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Registered trials
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