Evidence map›Paper›PMID 34278166›Full record

ArticleHepatology communications2021

Identification of Quantifiable Predictors of Relapse in Patients with Alcohol-Associated Liver Disease.

Nicole T Shen, Alyson Kaplan, Khalid Fahoum, Elora Basu, Akhil Shenoy, Nabeel Wahid, Amanda Ivatorov, Joseph Pisa, Annaheta Salajegheh, Enad Dawod and 4 more

Open access · goldAbstract read
In one paragraph

Article in Hepatology communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Nicole T ShenDivision of Gastroenterology and HepatologyWeill Cornell MedicineNew YorkNYUSA.
Alyson KaplanDivision of Gastroenterology and HepatologyWeill Cornell MedicineNew YorkNYUSA.
Khalid FahoumDepartment of MedicineWeill Cornell MedicineNew YorkNYUSA.
Elora BasuDepartment of MedicineWeill Cornell MedicineNew YorkNYUSA.
Akhil ShenoyDepartment of PsychiatryColumbia University Medical CenterNew YorkNYUSA.
Nabeel WahidDivision of General Internal MedicineWeill Cornell MedicineNew YorkNYUSA.
Amanda IvatorovDivision of Gastroenterology and HepatologyWeill Cornell MedicineNew YorkNYUSA.
Joseph PisaDivision of Gastroenterology and HepatologyWeill Cornell MedicineNew YorkNYUSA.
Annaheta SalajeghehDepartment of PsychiatryWeill Cornell MedicineNew YorkNYUSA.
Enad DawodDivision of Gastroenterology and HepatologyWeill Cornell MedicineNew YorkNYUSA.
Russell RosenblattDivision of Gastroenterology and HepatologyWeill Cornell MedicineNew YorkNYUSA.ORCID 0000-0003-3981-7053
Brett FortuneDivision of Gastroenterology and HepatologyWeill Cornell MedicineNew YorkNYUSA.ORCID 0000-0002-0646-467
Monika SaffordDivision of General Internal MedicineWeill Cornell MedicineNew YorkNYUSA.
Robert S BrownDivision of Gastroenterology and HepatologyWeill Cornell MedicineNew YorkNYUSA.
Cornell University · USColumbia University Irving Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abstinence in patients with alcohol-associated liver disease (ALD) reduces mortality. Most predictors of relapse are not quantifiable, preventing objective analysis of relapse risk and targeted intervention to improve clinical outcomes. We prospectively enrolled patients with ALD from November 2016 to December 2019 and administered a survey with two previously published scales to assess insight into alcohol-use disorder (Hanil Alcohol Insight Scale [HAIS]) and social support (Community Assessment Inventory Scale [CAIS]). Relapse was assessed using surveys and metabolite testing. Unadjusted and prespecified adjusted regression analyses identified predictors of relapse. We enrolled 81% of eligible patients (n = 136), of whom 58 had follow-up data available at the time of analysis. Over a median follow-up of 1 year (interquartile range: 0.5-1.4), 10 patients relapsed (17%). Patients who relapsed were more likely to continue drinking despite either a diagnosis of liver disease or a decompensating event, and were less likely to have been transplanted (all

Identifiers

PMID34278166
PMCPMC8279469
OpenAlexW3136938553

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.