Evidence map›Paper›PMID 34278158›Full record

ArticleACS omega2021

Real-Time Detection of State Transitions in Stochastic Signals from Biological Systems.

Max H Bergkamp, Leo J van IJzendoorn, Menno W J Prins

Abstract read
In one paragraph

Article in ACS omega, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Max H BergkampDepartment of Biomedical Engineering, Eindhoven University of Technology, Eindhoven 5612, The Netherlands.ORCID https://orcid.org/0000-0001-8904-4322
Leo J van IJzendoornDepartment of Applied Physics, Eindhoven University of Technology, Eindhoven 5612, The Netherlands.
Menno W J PrinsDepartment of Biomedical Engineering, Eindhoven University of Technology, Eindhoven 5612, The Netherlands.ORCID https://orcid.org/0000-0002-9788-7298

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Robust analysis of signals from stochastic biomolecular processes is critical for understanding the dynamics of biological systems. Measured signals typically show multiple states with heterogeneities and a wide range of state lifetimes. Here, we present an algorithm for robust detection of state transitions in experimental time traces where the properties of the underlying states are

Identifiers

PMID34278158
PMCPMC8280633

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.