ArticleEndocrinology, diabetes & metabolism2021
Hospitalization for hypoglycaemia in people with diabetes in Denmark, 1997-2017: Time trends in incidence and HbA
Article in Endocrinology, diabetes & metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed, 4 citations in OpenAlex.
- Declining incidence of hypoglycaemia in diabetes secondary to chronic pancreatitis: A nationwide cohort study from 2003 to 2022.Diabetes, obesity & metabolism · 2025Article
- Medication-Related Hospital Admissions and Emergency Department Visits in Older People with Diabetes: A Systematic Review.Journal of clinical medicine · 2024Review
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5 authors at 1 institution in 1 country.
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Abstract
objectiveTo assess incidence trends of first hospitalization for hypoglycaemia in Denmark and to examine HbA RESEARCH DESIGN AND
methodsWe performed a population-based study linking diagnosis, prescription and laboratory data. Standardized incidence of first hospitalization for hypoglycaemia in Denmark was assessed for each calendar year 1997-2017. HbA1c and glucose-lowering drug use was compared with age- and sex-matched diabetes comparisons without hospitalization for hypoglycaemia.
resultsThe annual age- and sex-standardized incidence rate of first hospitalization for hypoglycaemia per 100,000 person-years increased during 1997-2003 (from 17.7 to 30.3 per 100,000 person-years), remained stable until 2010 (30.4) and gradually declined until 2017 (22.0). During this period, we identified 3,479 people with type 1 diabetes and 15,329 people with type 2 diabetes experiencing first hospitalization for hypoglycaemia. Both diabetes groups experienced a mean HbA1c decrease of ~12%-15% in the months preceding first hospitalization, followed by a gradually increasing HbA1c afterwards. People with type 1 diabetes and hospitalization used similar insulin therapies as those without hospitalization. People with type 2 diabetes and hospitalization more often received insulin (55%) than comparisons (45%), and 45% discontinued insulin or stopped all glucose-lowering therapy after first hospitalization.
conclusionsIncidence of hospitalizations for hypoglycaemia has declined by one fourth the last decade in the Danish population. A HbA1c decrease precedes first hospitalization for hypoglycaemia in individuals with diabetes, and profound changes in glucose-lowering drug therapy for type 2 diabetes occur after hospitalization.
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