Evidence map›Paper›PMID 34277956›Full record

ArticleHealth science reports2021

A cross-sectional study on evaluation of complete blood count-associated parameters for the diagnosis of acute appendicitis.

Leila Haji Maghsoudi, Kourosh Kabir, Ali Soltanian, Haleh Pak, Mojtaba Ahmadinejad, Arghavan Khas Ahmadi

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Article in Health science reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5 citing papers in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Leila Haji MaghsoudiDepartment of Surgery, School of Medicine, Shahid Madani Hospital Alborz University of Medical Sciences Karaj Iran.
Kourosh KabirDepartment of Community Medicine and Epidemiology, School of Medicine, Social Determinants of Health Research Center Alborz University of Medical Sciences Karaj Iran.
Ali SoltanianDepartment of Surgery, School of Medicine Alborz University of Medical Sciences Karaj Iran.
Haleh PakDepartment of Surgery, School of Medicine, Shahid Madani Hospital Alborz University of Medical Sciences Karaj Iran.
Mojtaba AhmadinejadDepartment of Surgery, School of Medicine, Shahid Madani Hospital Alborz University of Medical Sciences Karaj Iran.ORCID https://orcid.org/0000-0001-9813-5912
Arghavan Khas AhmadiStudent Research Committee Alborz University of Medical Sciences Alborz Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsAcute appendicitis is one of the common causes of abdominal surgeries, however, the rate of negative appendectomy is as high as 20% as the diagnosis of appendicitis is challenging. The study aimed to evaluate complete blood count (CBC)-associated parameters among positive and negative appendectomy patients and determine their diagnostic importance.

methodsIn this cross-sectional study, patients who suspected of acute appendicitis were included. Preoperative blood samples taken from these patients for a complete blood count. Following parameters evaluated from their CBC: white blood cell (WBC), platelet (PLT), mean platelet volume (MPV), neutrophils-to-lymphocytes ratio, platelets-to-lymphocytes ratio, red cell distribution width (RDW), and platelet distribution width (PDW). These parameters analyzed for the positive and negative appendectomy patients using statistical analysis.

resultsOf 200 patients included in the study, 30 patients (15%) underwent negative appendectomy. The mean neutrophils, WBC, red blood cells, neutrophils-to-lymphocytes, and platelets-to-lymphocytes ratio was significantly high among positive appendectomy patients, (

conclusionThe findings of our study indicate that neutrophils-to-lymphocytes ratio alone is not sufficient for preoperative diagnosis of acute appendicitis and other CBC-related parameters did not have good sensitivity and specificity. Further studies are therefore required in this area.

Indexed as

acute appendicitisappendectomyCBClymphocytesneutrophilsparameters

Identifiers

PMID34277956
PMCPMC8279215

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