Evidence map›Paper›PMID 34277869›Full record

ArticleReports of biochemistry & molecular biology2021

Molecular Expression of Some Oncogenes and Predisposing Behaviors Contributing to the Aggressiveness of Prostate Cancer.

Mohammad Ghasem Kashanizadeh, Fariba Rezaei Fakhrnezhad, Saeede Yavari, Homa Alizadeh, Payam Hashemim, Amir Monfaredan

Open access · goldAbstract read
In one paragraph

Article in Reports of biochemistry & molecular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 1 country.

Mohammad Ghasem KashanizadehAzad University of Medical Sciences, Tehran, Iran.
Fariba Rezaei FakhrnezhadDepartment of Biotechnology, Faculty of Biological Sciences, Alzahra University, Tehran, Iran.
Saeede YavariScience and Research Branch, Department of Biology, Islamic Azad University, Tehran, Iran.
Homa AlizadehDepartment of Genetics, Faculty of Biological Sciences, Islamic Azad University North Tehran Branch, Tehran, Iran.
Payam HashemimFaculty of Medicine, Tehran University of Medical Science, Tehran, Iran.
Amir MonfaredanDepartment of Hematology, Faculty of Medicine, Tabriz Branch, Islamic Azad University, Tabriz, Iran.
Alzahra University · IRIslamic Azad University Medical Branch of Tehran · IRIslamic Azad University North Tehran Branch · IRIslamic Azad University of Tabriz · IRIslamic Azad University, Science and Research Branch · IRUniversity of Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProstate cancer is the second most common cancer in men in Iran. It can be treated in the early stages of the disease; therefore, early diagnosis can be lifesaving. The aim of this study was to investigate the molecular expression of some oncogenes and predisposing behaviors contributing to the aggressiveness of prostate cancer.

methodsIn this case-control study, prostate cancer specimens were collected from both patients and healthy volunteers. Several factors such as age, family history, smoking, and stage of the disease, were investigated based on the criteria of this study. Real-time PCR was used to measure the expression of four oncogenes. Statistical analysis of our data was carried out using SPSS software version 22.

resultsThe X

conclusionOverall, functional interpretation of gene expression in the prostate tissue can affect tumor progression. Yet, further practical studies are required to reveal the accurate underlying mechanisms.

Indexed as

AgeFamily HistoryOncogenesProstate CancerSmoking

Identifiers

PMID34277869
PMCPMC8279708
OpenAlexW3161750653

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.