ArticleJournal of arthropod-borne diseases2021
The Effect of Different Doses of Mesobuthus eupeus (Scorpionida: Buthidae) Scorpion Venom on the Production of Liver Necrosis in Nmri Mice.
Article in Journal of arthropod-borne diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundScorpion venom has a variety of different components considerably. Some of these compounds are proteins such as Phospholipase A2 which is one of the most important. Use of scorpion venom for the treatment of any disease requires an initial study to determine the therapeutic dose or safe dose. Therefore, due to the necessity of studying scorpion venom, it is of special importance to study the effects of its dose response in animal tissues.
methodsTo determine the inflammatory effects of scorpion's venom (
resultsThere was a significant differences between the test and control groups (in most groups). Liver necrosis was one of the important symptoms in this study, the severity of which was measured and statistically analyzed.
conclusionIt was determined that 0.05ppm is a safe dose and sub-lethal doses can use for the investigation of therapeutic effects of venom on cancer, diabetes, dermatitis, and so on.
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