ReviewAnnals of translational medicine2021
Surgical treatment of locally recurrent rectal cancer: a narrative review.
Review in Annals of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- The role of particle therapy in the treatment of locally recurrent rectal cancer: a systematic review.Radiology and oncology · 2026Pooled it
- Evolution of Prognosis and Management in Curative Treatment of Locally Recurrent Rectal Cancer: A Comprehensive Analysis from 2000 to 2023.Annals of surgical oncology · 2026Article
- Current clinical practice of radiotherapy for the non-operative treatment of patients with unresectable locally recurrent rectal cancer: results of a national survey of the dutch society for radiotherapy and oncology.Radiation oncology (London, England) · 2026Article
- A study of factors influencing access to MDT among patients with stage III to stage IV colorectal cancer: a national multicenter survey.Frontiers in oncology · 2026Article
- Neoadjuvant chemo-reirradiation followed by resection and intraoperative electron beam radiotherapy: outcomes of multimodality treatment for locally recurrent rectal cancer.Radiation oncology (London, England) · 2025Article
- Prospective radiotherapy quality Assurance leads to delineation guideline refinements for recurrent rectal cancer: Experience from the PelvEx II study.Clinical and translational radiation oncology · 2025Article
- Recurrence patterns and management of locally recurrent rectal cancer: a retrospective cohort study.Langenbeck's archives of surgery · 2025Article
- Surgical Outcomes of Retrorectal Tumors: A Retrospective Study of 12 Years' Experience.World journal of plastic surgery · 2025Article
- Current Management of Locally Recurrent Rectal Cancer.Cancers · 2024Review
- Post-operative complications following dose adaptation of intra-operative electron beam radiation therapy in locally advanced or recurrent rectal cancer.Journal of contemporary brachytherapy · 2024Article
- Review
- Use of Image-Guided Surgical Navigation during Resection of Locally Recurrent Rectal Cancer.Life (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo summarize the recent literature on surgical treatment of locally recurrent rectal cancer (LRRC).
backgroundLRRC is a heterogeneous disease that requires a multidisciplinary treatment approach. The treatment and prognosis depend on the site and type of recurrence. Radical resection remains the primary method for achieving long-term survival and improving symptom control. Preoperative chemoradiotherapy can reduce tumor volume and improve the R0 resection rate. Surgeons must clearly understand pelvic anatomy, develop a detailed preoperative plan, adopt a multidisciplinary approach for the surgical resection of the tumor as well as any invaded soft tissues, vessels, and bones, and ensure proper reconstruction. However, extended radical surgery often leads to a higher risk of postoperative complications and a low quality of life.
methodsWe searched English-language articles with keywords "locally recurrent rectal cancer", "surgery" and "multidisciplinary team" in PubMed published between January 2000 to October 2020.
conclusionsLRRC is a complex problem. Long-term survival is not impossible following multidisciplinary treatment in appropriately selected LRRC patients. The management of LRRC relies on a specialist team that determines the biological behavior of the tumor and evaluates treatment options through multidisciplinary discussions, thereby balancing the surgical costs and benefits, alleviating postoperative complications, and improving patients' quality of life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.