Evidence map›Paper›PMID 34277786›Full record

ArticleAnnals of translational medicine2021

High expression of PYCARD is an independent predictor of unfavorable prognosis and chemotherapy resistance in glioma.

Aijun Liang, Shupeng Zhong, Bin Xi, Chaoyang Zhou, Xingxing Jiang, Ronglan Zhu, Yu Yang, Liangchen Zhong, Dengfeng Wan

Open access · diamondAbstract read
In one paragraph

Article in Annals of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Aijun LiangDepartment of Neurosurgery, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, China.
Shupeng ZhongDepartment of Oncology, Zhongshan City People's Hospital, Zhongshan, China.
Bin XiDepartment of Neurosurgery, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, China.
Chaoyang ZhouDepartment of Neurosurgery, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, China.
Xingxing JiangDepartment of Neurosurgery, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, China.
Ronglan ZhuDepartment of Neurosurgery, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, China.
Yu YangDepartment of Neurosurgery, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, China.
Liangchen ZhongDepartment of Neurosurgery, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, China.
Dengfeng WanDepartment of Neurosurgery, Jiangxi Provincial People's Hospital Affiliated to Nanchang University, Nanchang, China.
Jiangxi Provincial People's Hospital · CNNanchang University · CNZhongshan People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsGlioma-resistant cells were compared with parental cells based on the GSE53014 and GSE113510 data sets. The relationship between

resultsElevated expression of

conclusionsHigh expression of

Indexed as

chemotherapy resistanceglioblastoma multiforme (GBM)long noncoding RNAs (lncRNAs)low grade glioma (LGG)PYD and CARD domain-containing (PYCARD)

Identifiers

PMID34277786
PMCPMC8267320
OpenAlexW3175485015

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.