ReviewFrontiers in cardiovascular medicine2021
Energy Drink-Associated Electrophysiological and Ischemic Abnormalities: A Narrative Review.
Review in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 37 citations in OpenAlex.
- Energy Drinks Decrease Left Ventricular Efficiency in Healthy Children and Teenagers: A Randomized Trial.Sensors (Basel, Switzerland) · 2022Trial
- Trial
- Sudden cardiac arrest in young adults: A comprehensive systematic review of epidemiology, aetiology and preventive strategies.Heart international · 2026Review
- Chronic high consumption of energy drinks and cardiovascular risk in adolescents-results of the EDKAR-study.European journal of epidemiology · 2025Article
- Energy Drink Exposures and Trends in Children and Young Adults Reported to the National Poison Data System.Progress in pediatric cardiology · 2025Article
- Article
- Patterns of Energy Drink Use, Risk Perception, and Regulatory Attitudes in the Adult Polish Population: Results of a Cross-Sectional Survey.Nutrients · 2025Article
- Decoding event-related potentials: single-dose energy dietary supplement acts on earlier brain processes than we thought.Frontiers in neuroinformatics · 2025Article
- Association between energy drink consumption, and substance use among adolescents: a cross sectional study.Frontiers in nutrition · 2025Article
- Article
- Histopathological Changes in the Myocardium Caused by Energy Drinks and Alcohol in the Mid-term and Their Effects on Skeletal Muscle Following Ischemia-reperfusion in a Rat Model.Anatolian journal of cardiology · 2023Article
- Energy drinks at adolescence: Awareness or unawareness?Frontiers in behavioral neuroscience · 2023Review
- Editorial: Alcohol and energy drinks: is this a really good mix?Frontiers in behavioral neuroscience · 2023Article
- Energy Drinks: Effects on Blood Pressure and Heart Rate in Children and Teenagers. A Randomized Trial.Frontiers in cardiovascular medicine · 2022Article
- Acute Myocardial Infarction Following the Consumption of Energy Drink in a 28-Year-Old Male: A Case Report.Journal of investigative medicine high impact case reportsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An increasing number of cardiovascular adverse effects, emergency room visits, and deaths have been linked to energy drinks. In this review, we summarized available published literature assessing electrophysiological and ischemic adverse effects associated with energy drink consumption. Overall, 32 case reports and 19 clinical trials are included in this review. Ventricular arrhythmia, supraventricular arrhythmia, and myocardial ischemia were amongst the most commonly reported in case reports with 3 having a fatal outcome. Although serious ischemic changes, arrhythmias, or death were not observed in clinical trials, significant electrophysiological changes, such as PR/PQ interval shortening/prolongation, QT/QTc shortening/prolongation, and ST-T changes, were noted. QT/QTc interval prolongation appears to be the most significant finding in clinical trials, and there appears to be a dose-response relationship between energy drink consumption and QTc prolongation. The exact mechanisms and the particular combination of ingredients behind energy drink-induced cardiac abnormalities require further evaluation. Until more information is available, energy drink use should be considered as part of the differential diagnosis in appropriate patients presenting with electrocardiographic changes. Further, certain patient populations should exercise caution and limit their energy drink consumption.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.