Evidence map›Paper›PMID 34277727›Full record

ArticleFrontiers in cardiovascular medicine2021

Effect of Patient-Specific Coronary Flow Reserve Values on the Accuracy of MRI-Based Virtual Fractional Flow Reserve.

Jackson Hair, Lucas Timmins, Retta El Sayed, Habib Samady, John Oshinski

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Systematic review and meta-analysis of Murray's law in the coronary arterial circulation.American journal of physiology. Heart and circulatory physiology · 2024
    Pooled it
  2. Coronary flow reserve evaluated by phase-contrast cine cardiovascular magnetic resonance imaging of coronary sinus: a meta-analysis.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Pooled it
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jackson HairDepartment of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, United States.
Lucas TimminsDepartment of Biomedical Engineering, University of Utah, Salt Lake City, UT, United States.
Retta El SayedDepartment of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, United States.
Habib SamadyDivision of Cardiology, Department of Medicine, Emory School of Medicine, Atlanta, GA, United States.
John OshinskiDepartment of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, United States.

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Biomechanical Indices for Coronary Lesion Rupture Risk and Lesion PrognosticationR01HL150608 · NHLBI · UNIVERSITY OF UTAH · PI HSU, EDWARD W, TIMMINS, LUCAS H. · 2020 to 2024
$1.7M
Coronary Fractional Flow Reserve Determined Using MRI and CFDR01EB027774 · NIBIB · EMORY UNIVERSITY · PI OSHINSKI, JOHN N · 2020 to 2025
$1.7M
NCATS NIH HHS UL1 TR002378NHLBI NIH HHS R01 HL150608NIBIB NIH HHS R01 EB027774
6 · The paper itself

Abstract

The purpose of this study is to investigate the effect of varying coronary flow reserve (CFR) values on the calculation of computationally-derived fractional flow reserve (FFR). CFR reflects both vessel resistance due to an epicardial stenosis, and resistance in the distal microvascular tissue. Patients may have a wide range of CFR related to the tissue substrate that is independent of epicardial stenosis levels. Most computationally based virtual FFR values such as FFR

Indexed as

CFDCFRFFRMRIvFFR

Identifiers

PMID34277727
PMCPMC8282891

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.