Evidence map›Paper›PMID 34277510›Full record

ReviewClinical and translational imaging2021

State of the art of

Massimiliano Casali, Chiara Lauri, Corinna Altini, Francesco Bertagna, Gianluca Cassarino, Angelina Cistaro, Anna Paola Erba, Cristina Ferrari, Ciro Gabriele Mainolfi, Andrea Palucci and 26 more

Abstract readReview
In one paragraph

Review in Clinical and translational imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Diagnostic value of [European journal of nuclear medicine and molecular imaging · 2026
    Pooled it
  2. EANM/SNMMI guideline/procedure standard for [European journal of nuclear medicine and molecular imaging · 2025
    Guideline
  3. Pooled it
  4. Pooled it
  5. Review
  6. Article
  7. Article
  8. Article
  9. [Annals of nuclear medicine · 2026
    Article
  10. Clinical Evaluation of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  11. Article
  12. Discriminating inflammation from malignancy with short-dynamic patlak parametric 18 F-FDG PET/CT.European journal of nuclear medicine and molecular imaging · 2026
    Article
  13. Targeting the polyene chain represents an adjuvant strategy for optimizing polyene antifungals.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  14. [EJNMMI research · 2026
    Article
  15. Article
  16. Article
  17. Article
  18. Advancing cardiac tumor diagnosis: evaluatingAmerican journal of cardiovascular disease · 2026
    Review
  19. Clinical Features and Diagnostic Challenges ofInfection and drug resistance · 2026
    Article
  20. Combined [European journal of nuclear medicine and molecular imaging · 2026
    Observational

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

36 authors.

Massimiliano Casali *Nuclear Medicine Unit, Azienda Unità Sanitaria Locale IRCCS, Reggio Emilia, Italy.ORCID 0000-0003-3832-8696
Chiara Lauri *Nuclear Medicine Unit, Department of Medical-Surgical Sciences and of Translational Medicine, "Sapienza" University of Rome, Rome, Italy.
Corinna Altini *Nuclear Medicine Unit, Interdisciplinary Department of Medicine, University of Bari, Bari, Italy.
Francesco Bertagna *Nuclear Medicine, University of Brescia and Spedali Civili di Brescia, Brescia, Italy.
Gianluca Cassarino *Nuclear Medicine Unit, Department of Medicine DIMED, University of Padova, Padova, Italy.
Angelina Cistaro *Department of Nuclear Medicine, Ospedali Galliera, Genoa, Italy.
Anna Paola Erba *Regional Center of Nuclear Medicine, Department of Translational Research and Advanced Technologies in Medicine, University of Pisa, Pisa, Italy.
Cristina Ferrari *Nuclear Medicine Unit, Interdisciplinary Department of Medicine, University of Bari, Bari, Italy.
Ciro Gabriele Mainolfi *Department of Advanced Biomedical Sciences, University "Federico II", Naples, Italy.
Andrea Palucci *Department of Nuclear Medicine, "Ospedali Riuniti di Torrette" Hospital, Ancona, Italy.
Napoleone Prandini *Nuclear Medicine Unit, Department of Diagnostic Imaging, Centro Diagnostico Italiano, Milan, Italy.
Sergio BaldariNuclear Medicine Unit, Department of Biomedical and Dental Sciences and of Morpho-Functional Imaging, University of Messina, Messina, Italy.
Francesco BartoliRegional Center of Nuclear Medicine, Department of Translational Research and Advanced Technologies in Medicine, University of Pisa, Pisa, Italy.
Mirco BartolomeiNuclear Medicine Unit, Oncological Medical and Specialists Department, University Hospital of Ferrara, Ferrara, Italy.
Adriana D'AntonioDepartment of Advanced Biomedical Sciences, University "Federico II", Naples, Italy.
Francesco DondiNuclear Medicine, University of Brescia and Spedali Civili di Brescia, Brescia, Italy.
Patrizia GandolfoNuclear Medicine Unit, Department of Diagnostic Imaging, Centro Diagnostico Italiano, Milan, Italy.
Alessia GiordanoDepartment of Advanced Biomedical Sciences, University "Federico II", Naples, Italy.
Riccardo LaudicellaNuclear Medicine Unit, Department of Biomedical and Dental Sciences and of Morpho-Functional Imaging, University of Messina, Messina, Italy.
Michela MassolloDepartment of Nuclear Medicine, Ospedali Galliera, Genoa, Italy.
Alberto NieriNuclear Medicine Unit, Oncological Medical and Specialists Department, University Hospital of Ferrara, Ferrara, Italy.
Arnoldo PiccardoDepartment of Nuclear Medicine, Ospedali Galliera, Genoa, Italy.
Laura VendraminNuclear Medicine Unit, Department of Medicine DIMED, University of Padova, Padova, Italy.
Francesco MuratoreRheumatology Unit, Azienda Unità Sanitaria Locale IRCCS, Reggio Emilia, Italy.
Valentina LavelliNuclear Medicine Unit, Interdisciplinary Department of Medicine, University of Bari, Bari, Italy.
Domenico Albano *Nuclear Medicine, University of Brescia and Spedali Civili di Brescia, Brescia, Italy.
Luca Burroni *Department of Nuclear Medicine, "Ospedali Riuniti di Torrette" Hospital, Ancona, Italy.
Alberto Cuocolo *Department of Advanced Biomedical Sciences, University "Federico II", Naples, Italy.
Laura Evangelista *Nuclear Medicine Unit, Department of Medicine DIMED, University of Padova, Padova, Italy.
Elena Lazzeri *Regional Center of Nuclear Medicine, Department of Translational Research and Advanced Technologies in Medicine, University of Pisa, Pisa, Italy.
Natale Quartuccio *Nuclear Medicine Unit, A.R.N.A.S. Civico di Cristina and Benfratelli Hospitals, Palermo, Italy.
Brunella Rossi *Nuclear Medicine Unit, Department of Services, ASUR MARCHE-AV5, Ascoli Piceno, Italy.
Giuseppe Rubini *Nuclear Medicine Unit, Interdisciplinary Department of Medicine, University of Bari, Bari, Italy.
Martina Sollini *Humanitas Clinical and Research Center, IRCCS, Rozzano, Italy.
Annibale Versari *Nuclear Medicine Unit, Azienda Unità Sanitaria Locale IRCCS, Reggio Emilia, Italy.
Alberto Signore *Nuclear Medicine Unit, Department of Medical-Surgical Sciences and of Translational Medicine, "Sapienza" University of Rome, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe diagnosis, severity and extent of a sterile inflammation or a septic infection could be challenging since there is not one single test able to achieve an accurate diagnosis. The clinical use of 18F-fluorodeoxyglucose ([

methodsIn September 2020, the inflammatory and infectious diseases focus group (IIFG) of the Italian Association of Nuclear Medicine (AIMN) proposed to realize a procedural paper about the clinical applications of [

resultsOverall, we summarized 291 scientific papers and guidelines published between 1998 and 2021. Papers were divided in several sub-topics and summarized in the following paragraphs: clinical indications, image interpretation criteria, future perspectivess and new trends (for each single disease), while patient preparation, image acquisition, possible pitfalls and reporting modalities were described afterwards. Moreover, a specific section was dedicated to pediatric and PET/MRI indications. A collection of images was described for each indication.

conclusionsCurrently, [ SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s40336-021-00445-w.

Indexed as

FDGImagingInfectionInflammationPET

Identifiers

PMID34277510
PMCPMC8271312

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.