Evidence map›Paper›PMID 34277443›Full record

ArticleFrontiers in oncology2021

Crosstalk Between DNA Methylation and Gene Mutations in Colorectal Cancer.

Maria Dobre, Alessandro Salvi, Iulia Andreea Pelisenco, Florina Vasilescu, Giuseppina De Petro, Vlad Herlea, Elena Milanesi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  7. The role of Pcdh10 in neurological disease and cancer.Journal of cancer research and clinical oncology · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Nanotechnology for colorectal cancer detection and treatment.World journal of gastroenterology · 2022
    Review
  13. Article
  14. Promoter methylation analysis ofAsian biomedicine : research, reviews and news · 2022
    Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Maria DobreLaboratory of Histopathology and Immunohistochemistry, Victor Babes National Institute of Pathology, Bucharest, Romania.
Alessandro SalviDivision of Biology and Genetics, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Iulia Andreea PelisencoFaculty of Biology, University of Bucharest, Bucharest, Romania.
Florina VasilescuLaboratory of Histopathology and Immunohistochemistry, Victor Babes National Institute of Pathology, Bucharest, Romania.
Giuseppina De PetroDivision of Biology and Genetics, Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Vlad HerleaDepartment of Pathology, Fundeni Clinical Institute, Bucharest, Romania.
Elena MilanesiLaboratory of Radiobiology, Victor Babes National Institute of Pathology, Bucharest, Romania.
Institutul National Victor Babes · ROUniversity of Brescia · ITInstitutul Clinic Fundeni · ROUniversity of Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is often characterized by mutations and aberrant DNA methylation within the promoters of tumor suppressor genes and proto-oncogenes. The most frequent somatic mutations occur within

Indexed as

BRAFcolorectal cancerDNA methylationKRASmutations

Identifiers

PMID34277443
PMCPMC8281955
OpenAlexW3184761728

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.