Evidence map›Paper›PMID 34277435›Full record

ArticleFrontiers in oncology2021

Feiyanning Formula Induces Apoptosis of Lung Adenocarcinoma Cells by Activating the Mitochondrial Pathway.

Li-Min Zhu, Hai-Xia Shi, Masahiro Sugimoto, Kenjiro Bandow, Hiroshi Sakagami, Shigeru Amano, Hai-Bin Deng, Qing-Yu Ye, Yun Gai, Xiao-Li Xin and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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  9. Mechanism ofEvidence-based complementary and alternative medicine : eCAM · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Li-Min ZhuDepartment of Oncology, LongHua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Hai-Xia ShiDepartment of Traditional Chinese Medicine, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Masahiro SugimotoResearch and Development Center for Minimally Invasive Therapies, Institute of Medical Science, Tokyo Medical University, Shinjuku, Japan.
Kenjiro BandowDivision of Biochemistry, Meikai University School of Dentistry, Saitama, Japan.
Hiroshi SakagamiMeikai University Research Institute of Odontology (M-RIO), Meikai University School of Dentistry, Saitama, Japan.
Shigeru AmanoMeikai University Research Institute of Odontology (M-RIO), Meikai University School of Dentistry, Saitama, Japan.
Hai-Bin DengDepartment of Oncology, LongHua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Qing-Yu YeDepartment of Oncology, LongHua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Yun GaiDepartment of Oncology, The Seventh People's Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Xiao-Li XinDepartment of Oncology, LongHua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zhen-Ye XuDepartment of Oncology, LongHua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Longhua Hospital Shanghai University of Traditional Chinese Medicine · CNMeikai University · JPShanghai University of Traditional Chinese Medicine · CNShanghai Ninth People's Hospital · CNTokyo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Feiyanning formula (FYN) is a traditional Chinese medicine (TCM) prescription used for more than 20 years in the treatment of lung cancer. FYN is composed of

Indexed as

A549 cellsapoptosisATP utilizationFYNmetabolomics analysismitochondrial pathwayNSCLC

Identifiers

PMID34277435
PMCPMC8284078
OpenAlexW3184463737

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.