Evidence map›Paper›PMID 34277402›Full record

ArticleFrontiers in oncology2021

Exploring the Significance of the Exon 4-Skipping Isoform of the ZNF217 Oncogene in Breast Cancer.

Aurélie Bellanger, Diep T Le, Julie Vendrell, Anne Wierinckx, Lőrinc S Pongor, Jérôme Solassol, Joël Lachuer, Philippe Clezardin, Balázs Győrffy, Pascale A Cohen

Abstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aurélie BellangerUniversité Lyon 1, Lyon, France.
Diep T LeUniversité Lyon 1, Lyon, France.
Julie VendrellDépartement de Pathologie et Oncobiologie, Laboratoire de Biologie des Tumeurs Solides, CHU Montpellier, Univ. Montpellier, Montpellier, France.
Anne WierinckxUniversité Lyon 1, Lyon, France.
Lőrinc S PongorDepartment of Bioinformatics, Semmelweis University, Budapest, Hungary.
Jérôme SolassolDépartement de Pathologie et Oncobiologie, Laboratoire de Biologie des Tumeurs Solides, CHU Montpellier, Univ. Montpellier, Montpellier, France.
Joël LachuerUniversité Lyon 1, Lyon, France.
Philippe ClezardinUniversité Lyon 1, Lyon, France.
Balázs GyőrffyDepartment of Bioinformatics, Semmelweis University, Budapest, Hungary.
Pascale A CohenUniversité Lyon 1, Lyon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oncogene alternative splicing events can create distinct functional transcripts that offer new candidate prognostic biomarkers for breast cancer. ZNF217 is a well-established oncogene but its exon 4-skipping isoform (ZNF217-ΔE4) has never been investigated in terms of clinical or biological relevance. Using

Indexed as

breast cancerisoformprognosissplice variantZNF217

Identifiers

PMID34277402
PMCPMC8283766

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.