Evidence map›Paper›PMID 34277401›Full record

ArticleFrontiers in oncology2021

Long-Term Safety and Efficacy of CT-Guided I

Yuliang Jiang, Peng Zhen, Jinchao Dai, Yixing Li, Shifeng Liu, Junma Xu, Yufeng Wang, Suqing Tian, Yue Cui, Zhe Ji and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Utility of spectral CT with orthopedic metal artifact reduction algorithms forQuantitative imaging in medicine and surgery · 2024
    Article
  4. Article
  5. The efficacy and safety ofFrontiers in oncology · 2022
    Article
  6. A Case of Iodine 125 Seeds (I-125) Responding to Lung Squamous Cell Carcinoma.Dose-response : a publication of International Hormesis Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 1 country.

Yuliang JiangDepartment of Radiation Oncology, Peking University 3rdHospital, Beijing, China.
Peng ZhenDepartment of Radiation Oncology, Chifeng Cancer Hospital, Chifeng, China.
Jinchao DaiDepartment of Nuclear Medicine, Qingdao Central Hospital, Qingdao, China.
Yixing LiDepartment of Nuclear Medicine, Yichang First People's Hospital, Yichang, China.
Shifeng LiuDepartment of Interventional Radiology, Affiliated Hospital of Qingdao University, Qingdao, China.
Junma XuDepartment of Respiratory, Jintan District People's Hospital, Changzhou, China.
Yufeng WangDepartment of Nuclear Medicine, Xuzhou Cancer Hospital, Xuzhou, China.
Suqing TianDepartment of Radiation Oncology, Peking University 3rdHospital, Beijing, China.
Yue CuiDepartment of Radiation Oncology, Peking University 3rdHospital, Beijing, China.
Zhe JiDepartment of Radiation Oncology, Peking University 3rdHospital, Beijing, China.
Fuxin GuoDepartment of Radiation Oncology, Peking University 3rdHospital, Beijing, China.
Bin QiuDepartment of Radiation Oncology, Peking University 3rdHospital, Beijing, China.
Haitao SunDepartment of Radiation Oncology, Peking University 3rdHospital, Beijing, China.
Jinghong FanDepartment of Radiation Oncology, Peking University 3rdHospital, Beijing, China.
Junjie WangDepartment of Radiation Oncology, Peking University 3rdHospital, Beijing, China.
Peking University Third Hospital · CNPeking University · CNAffiliated Hospital of Qingdao University · CNChifeng Municipal Hospital · CNJintan People's Hospital · CNQingdao University · CNXuzhou Cancer Hospital · CNYichang Central People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the safety and efficacy of CT-guided I MATERIALS AND

methodsThis is a multicenter retrospective study of 113 patients (83 males; median age 57 years) with rHNSC who underwent CT-guided I

resultsDuring a median follow-up duration of 20 months (range, 3-152 months), 87 patients died. The 1-, 2-, 3-, and 5-year local control rate were 57.4%, 41.8%, 29.3%, and 15.2%, respectively. The median time to progression was 15 months [95% confidence interval (CI), 6.1-23.9 months]. The median overall survival (OS) was 20 months (95% CI, 12.4-27.6 months). The 1-, 2-, 3-, and 5-year OS rate were 63.6%, 44.6%, 29.9%, and 21.7%, respectively. Univariate and multivariate analyses revealed that KPS score and postoperative D90 were significantly associated with patients' OS. The complications were mainly grade I/II skin and mucosal reactions: 18 cases (15.9%) of grade I/II and eight cases (7.0%) of grade III radiation dermatitis, and 14 cases (12.4%) of grade I/II and three cases (2.7%) grade III mucosal reactions. No grade IV or severer complications were found.

conclusionCT-guided I

Indexed as

brachytherapyradioactive seed implantationradiotherapyrecurrent head and neck cancersquamous carcinoma

Identifiers

PMID34277401
PMCPMC8281320
OpenAlexW3182209599

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.