Evidence map›Paper›PMID 34277275›Full record

ArticleCureus2021

Psychiatric Comorbidities in Pediatric Inpatients With Human Immunodeficiency Virus Infection and Impact on Hospital Course: Inputs From a Case-Control Inpatient Study.

Caroline C Dias, Victoria Ayala, Fartun A Aliduux, Sayeda A Basith, Albulena Sejdiu, Miles M Nakaska, Sabiha Akter, Keerthika Mathialagan, Pradipta Majumder

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 59% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 6 countries.

Caroline C DiasPsychiatry, Yenepoya Medical College and Hospital, Mangalore, IND.
Victoria AyalaPsychiatry, Ross University School of Medicine, Bridgetown, BRB.
Fartun A AliduuxMedicine, Medical University of the Americas, Charlestown, KNA.
Sayeda A BasithPsychiatry and Behavioral Sciences, Medical University of the Americas, Charlestown, KNA.
Albulena SejdiuPsychiatry, Saints Cyril and Methodius University, Skopje, MKD.
Miles M NakaskaFamily Medicine, American University of the Caribbean, Calgary, CAN.
Sabiha AkterPsychiatry, Bergen New Bridge Medical Center, Paramus, USA.
Keerthika MathialaganPsychiatry, Sree Balaji Medical College and Hospital, Chennai, IND.
Pradipta MajumderPsychiatry, Drexel University College of Medicine, Philadelphia, USA.
Medical University of the Americas · KNRoss University School of Medicine · BBAmerican University of the Caribbean School of Medicine · SXDrexel University · USSree Balaji Dental College and Hospital · INWellSpan Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives In this study, we aimed to delineate psychiatric comorbidities in pediatric inpatients with versus without human immunodeficiency virus (HIV) infection and to measure its impact on the length of stay (LOS) and cost of treatment during hospitalization. Methodology We conducted a case-control study using the Nationwide Inpatient Sample and included 4,920 pediatric inpatients between the ages of six and 18 years who were sub-grouped by a comorbid diagnosis of HIV (N = 2,595) and non-HIV (N = 2,325) and matched for demographics (age, sex, and race) by propensity case-control matching. Logistic regression analyses were used to evaluate the adjusted odds ratio (aOR) of association for psychiatric comorbidities (depression, anxiety, post-traumatic stress disorder, psychosis, and drug abuse) in the HIV-positive compared with the HIV-negative (as reference category) pediatric inpatients. We measured the differences in the LOS and cost using the independent sample t-test. Results We found that the most prevalent psychiatric comorbidities in the HIV-positive group were anxiety (6.9%), drug abuse (6.6%), psychosis (6.4%), and depression (6.2%). The HIV-positive group had a significantly higher likelihood of comorbid psychosis (aOR: 1.82; 95% confidence interval [CI]: 1.38-2.40) and depression (aOR: 1.79; 95% CI: 1.36-2.36). The mean LOS per hospitalization episode was longer for the HIV-positive group (11.1 days vs. 6.0 days; P < 0.001) compared to the HIV-negative pediatric inpatients. Conclusions We found an increased risk of depression by 79% and psychosis by 82% in the HIV-positive pediatric population. These inpatients also had an extended hospitalization stay (by five days), adding to the healthcare economic burden.

Indexed as

adolescent healthdepressionhuman immunodeficiency virus infectionpsychiatric comorbiditiespsychosis

Identifiers

PMID34277275
PMCPMC8281798
OpenAlexW3169767808

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.