Evidence map›Paper›PMID 34277059›Full record

ArticleJournal of thoracic disease2021

MicroRNA-155-5p promotes cell proliferation and invasion in lung squamous cell carcinoma through negative regulation of fibroblast growth factor 9 expression.

Feng Liu, Qing Mao, Shaojin Zhu, Junlan Qiu

Open access · diamondAbstract read
In one paragraph

Article in Journal of thoracic disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Feng LiuDepartment of Cardiothoracic Surgery, Nanjing Lishui People's Hospital, Zhongda Hospital Lushui Branch Affiliated to Southeast University, Nanjing, China.
Qing MaoDepartment of Cardiothoracic Surgery, Nanjing Lishui People's Hospital, Zhongda Hospital Lushui Branch Affiliated to Southeast University, Nanjing, China.
Shaojin ZhuDepartment of Thoracic Surgery, The First Affiliated Hospital (Yijishan Hospital) of Wannan Medical College, Wuhu, China.
Junlan QiuDepartment of Oncology and Hematology, The Affiliated Suzhou Science and Technology Town Hospital of Nanjing Medical University, Suzhou, China.
Zhongda Hospital Southeast University · CNFirst Affiliated Hospital of Wannan Medical College · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNon-small cell lung cancer (NSCLC) ranks first for mortality among all malignancies. Squamous cell carcinoma (SCC) is one of the main types of NSCLC. Previous studies have found that fibroblast growth factor 9 (

methodsFluorescence quantitative polymerase chain reaction was employed for the detection miR-155-5p and

resultsThe results of fluorescence quantitative PCR revealed that miR-155-5p and

conclusionsOur results show that miR-155-5p, as an oncogene, negative regulates

Indexed as

FGF9invasionLung squamous cell carcinomamiR-155-5pproliferation

Identifiers

PMID34277059
PMCPMC8264708
OpenAlexW3175825441

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.