Evidence map›Paper›PMID 34277001›Full record

ArticleMolecular and clinical oncology2021

Clinical evaluation of RB1 genetic testing reveals novel mutations in Vietnamese patients with retinoblastoma.

Chinh Quoc Hoang, Hong-Quan Duong, Nguyen Thanh Nguyen, Sy Anh Hao Nguyen, Cuong Nguyen, Bo Duy Nguyen, Lan Tuyet Phung, Dung Thuy Nguyen, Chau Thi Minh Pham, Trang Le Doan and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Molecular and clinical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Chinh Quoc HoangVinmec Hi-Tech Center, Vinmec Healthcare System, Hanoi 100000, Vietnam.
Hong-Quan DuongDepartment of Cancer Research, Vinmec Research Institute of Stem Cell and Gene Technology, Hanoi 100000, Vietnam.
Nguyen Thanh NguyenDepartment of Translational Biomedical Informatics, Vingroup Big Data Institute, Hanoi 100000, Vietnam.
Sy Anh Hao NguyenInstitute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi 100000, Vietnam.
Cuong NguyenVinmec Hi-Tech Center, Vinmec Healthcare System, Hanoi 100000, Vietnam.
Bo Duy NguyenDepartment of Pediatrics 3, Vinmec International Hospital in Times City, Vinmec Healthcare System, Hanoi 100000, Vietnam.
Lan Tuyet PhungDepartment of Pediatrics 3, Vinmec International Hospital in Times City, Vinmec Healthcare System, Hanoi 100000, Vietnam.
Dung Thuy NguyenDepartment of Pediatrics 3, Vinmec International Hospital in Times City, Vinmec Healthcare System, Hanoi 100000, Vietnam.
Chau Thi Minh PhamDepartment of Pediatric Ophthalmology, Vietnam National Eye Hospital, Hanoi 100000, Vietnam.
Trang Le DoanDepartment of Pediatric Ophthalmology, Vietnam National Eye Hospital, Hanoi 100000, Vietnam.
Mai Hoang TranDepartment of Cancer Research, Vinmec Research Institute of Stem Cell and Gene Technology, Hanoi 100000, Vietnam.
Vinmec International Hospital · VNNational Hospital of Pediatrics · VNHanoi Medical University · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical evaluation of the genetic testing strategy is essential for ensuring the correct determination of mutation carriers. The current study retrospectively analyzed genetic and clinicopathological data from 62 Vietnamese patients with retinoblastoma (RB) referred to the Vinmec Hi-Tech Center for RB transcriptional corepressor 1 (

Indexed as

next generation sequencingnovel mutationsRB transcriptional corepressor 1retinoblastomarisk-stratified factorssensitivity

Identifiers

PMID34277001
PMCPMC8278403
OpenAlexW3174051698

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.