Evidence map›Paper›PMID 34276663›Full record

ArticleFrontiers in immunology2021

A Strong Synergy Between the Thiopeptide Bacteriocin Micrococcin P1 and Rifampicin Against MRSA in a Murine Skin Infection Model.

Kirill V Ovchinnikov, Christian Kranjec, Amar Telke, Morten Kjos, Tage Thorstensen, Siegfried Scherer, Harald Carlsen, Dzung B Diep

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
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  15. The Skin Microbiome: Current Landscape and Future Opportunities.International journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Kirill V OvchinnikovFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Christian KranjecFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Amar TelkeFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Morten KjosFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Tage ThorstensenARD Innovation AS, Ås, Norway.
Siegfried SchererTUM School of Life Sciences, Technical University of Munich, Munich, Germany.
Harald CarlsenFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Dzung B DiepFaculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, Ås, Norway.
Norwegian University of Life Sciences · NOTechnical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotic-resistant bacterial pathogens have become a serious threat worldwide. One of these pathogens is methicillin-resistant

Indexed as

Administration, CutaneousAnimalsAnti-Bacterial AgentsBacteriocinsDrug Resistance, Multiple, BacterialDrug SynergismDrug Therapy, CombinationFemaleMethicillin-Resistant Staphylococcus aureusMiceMice, Inbred BALB CMicrobial Sensitivity TestsRecurrenceRifampinStaphylococcal Skin InfectionsStaphylococcusAnti-Bacterial AgentsBacteriocinsmicrococcinRifampinbacteriocinmicrococcin P1MRSAmurine modelRifampi(ci)nskin infection bacteria

Identifiers

PMID34276663
PMCPMC8284338
OpenAlexW3183164273

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.