Evidence map›Paper›PMID 34276420›Full record

ArticleFrontiers in physiology2021

Prolonged Right Ventricular Outflow Tract Endocardial Activation Duration and Presence of Deceleration Zones in Patients With Idiopathic Premature Ventricular Contractions. Association With Low Voltage Areas.

Leonor Parreira, Pedro Carmo, Rita Marinheiro, Dinis Mesquita, José Farinha, Ana Esteves, Pedro Amador, António Ferreira, Marta Fonseca, Rui Caria and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Leonor ParreiraDepartment of Cardiology, Hospital Centre of Setubal, Setubal, Portugal.
Pedro CarmoDepartment of Cardiology, Luz Hospital Lisboa, Lisbon, Portugal.
Rita MarinheiroDepartment of Cardiology, Hospital Centre of Setubal, Setubal, Portugal.
Dinis MesquitaDepartment of Cardiology, Hospital Centre of Setubal, Setubal, Portugal.
José FarinhaDepartment of Cardiology, Hospital Centre of Setubal, Setubal, Portugal.
Ana EstevesDepartment of Cardiology, Hospital Centre of Setubal, Setubal, Portugal.
Pedro AmadorDepartment of Cardiology, Hospital Centre of Setubal, Setubal, Portugal.
António FerreiraDepartment of Cardiology, Luz Hospital Lisboa, Lisbon, Portugal.
Marta FonsecaDepartment of Cardiology, Hospital Centre of Setubal, Setubal, Portugal.
Rui CariaDepartment of Cardiology, Hospital Centre of Setubal, Setubal, Portugal.
Pedro AdragaoDepartment of Cardiology, Luz Hospital Lisboa, Lisbon, Portugal.
Hospital de São Bernardo · PTHospital da Luz · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsThe wavefront propagation velocity in the myocardium with fibrosis is characterized by the presence of deceleration zones and late activated zones, that are absent in the normal myocardium. Our aim was to study the right ventricular outflow tract (RVOT) endocardial activation duration in sinus rhythm, and assess the presence of deceleration zones, in patients with premature ventricular contractions (PVCs) and in controls.

methodsWe studied 29 patients with idiopathic PVCs from the outflow tract, subjected to catheter ablation that had an activation and voltage map of the RVOT in sinus rhythm. A control group of 15 patients without PVCs that underwent ablation of supraventricular arrhythmias was also studied. RVOT endocardial activation duration and number of 10 ms isochrones across the RVOT were assessed. Propagation speed was calculated at the zone with the higher number of isochrones per cm radius. Deceleration zones were defined as zones with >3 isochrones within 1 cm radius. Low voltage areas were defined as areas with local electrogram with amplitude <1.5 mV.

resultsThe two groups did not differ in relation to age, gender or number of points in the map. RVOT endocardial activation duration and number of 10 ms isochrones were higher in the PVC group; 56 (41-66) ms vs. 39 (35-41) ms,

conclusionRight ventricular outflow tract endocardial activation duration was longer, propagation speed was lower and deceleration zones were more frequent in patients with PVCs than in controls and were associated with the presence of low voltage areas.

Indexed as

deceleration zoneidiopathiclow voltage areaspremature ventricular beatright ventricular outflow tract

Identifiers

PMID34276420
PMCPMC8283314
OpenAlexW3155304483

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.