Evidence map›Paper›PMID 34276419›Full record

ArticleFrontiers in physiology2021

Murine Salivary Amylase Protects Against

David J Culp, Bently Robinson, Melanie N Cash

Abstract read
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Novel potential biomarkers for predicting childhood caries via metagenomic analysis.Frontiers in cellular and infection microbiology · 2025
    Article
  7. Unveiling the complexity of early childhood caries:Journal of oral microbiology · 2024
    Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

David J CulpDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL, United States.
Bently RobinsonDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL, United States.
Melanie N CashDepartment of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL, United States.

Funding

SALIVARY MUCOUS CELL GENE EXPRESSIONR01DE014730 · NIDCR · UNIVERSITY OF ROCHESTER · PI CULP, DAVID JOHN · 2003 to 2007
$1.8M
Oral Infectious Disease: Virulence and Host DeterminantsR01DE016362 · NIDCR · UNIVERSITY OF ROCHESTER · PI CULP, DAVID JOHN · 2005 to 2009
$1.7M
Oral Mucins as a Diagnostic Indicator and Therapeutic Treatment for XerostomiaR21DE020147 · NIDCR · UNIVERSITY OF FLORIDA · PI CULP, DAVID JOHN · 2010 to 2011
$282k
NIDCR NIH HHS R01 DE014730NIDCR NIH HHS R01 DE016362NIDCR NIH HHS R21 DE020147
6 · The paper itself

Abstract

Saliva protects dental surfaces against cavities (i. e., dental caries), a highly prevalent infectious disease frequently associated with acidogenic

Indexed as

aggregationanimal modelinfectious diseaseinnate immunitymicrobiomeStreptococcus

Identifiers

PMID34276419
PMCPMC8283412

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.