Evidence map›Paper›PMID 34276297›Full record

ArticleFrontiers in neuroscience2021

Giuseppe Uras, Alessia Manca, Pengfei Zhang, Zsuzsa Markus, Natalie Mack, Stephanie Allen, Marco Bo, Shengtao Xu, Jinyi Xu, Marios Georgiou and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Comparative study of rivastigmine and galantamine on the transgenicCurrent research in pharmacology and drug discovery · 2022
    Article
  6. Exploring Aβ Proteotoxicity and Therapeutic Candidates UsingInternational journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Giuseppe UrasDivision of Molecular Therapeutics and Formulation, School of Pharmacy, The University of Nottingham, University Park, Nottingham, United Kingdom.
Alessia MancaDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Pengfei ZhangState Key Laboratory of Natural Medicines, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, China.
Zsuzsa MarkusQueens Medical Centre, School of Life Sciences, The University of Nottingham, Nottingham, United Kingdom.
Natalie MackSchool of Biosciences, University of Nottingham, Nottingham, United Kingdom.
Stephanie AllenDivision of Molecular Therapeutics and Formulation, School of Pharmacy, The University of Nottingham, University Park, Nottingham, United Kingdom.
Marco BoDepartment of Biomedical Sciences, University of Sassari, Sassari, Italy.
Shengtao XuState Key Laboratory of Natural Medicines, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, China.
Jinyi XuState Key Laboratory of Natural Medicines, Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing, China.
Marios GeorgiouQueens Medical Centre, School of Life Sciences, The University of Nottingham, Nottingham, United Kingdom.
Zheying ZhuDivision of Molecular Therapeutics and Formulation, School of Pharmacy, The University of Nottingham, University Park, Nottingham, United Kingdom.
University of Nottingham · GBChina Pharmaceutical University · CNUniversity of Sassari · ITQueen's Medical Centre · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease is a neurodegenerative disease characterized by disrupted memory, learning functions, reduced life expectancy, and locomotor dysfunction, as a result of the accumulation and aggregation of amyloid peptides that cause neuronal damage in neuronal circuits. In the current study, we exploited a transgenic

Indexed as

acetylcholinesteraseacetylcholinesterase inhibitorsAlzheimer’s diseaseamyloid aggregation 3Aβ42Drosophila melanogaster

Identifiers

PMID34276297
PMCPMC8278008
OpenAlexW3164242747

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.