Evidence map›Paper›PMID 34276296›Full record

ArticleFrontiers in neuroscience2021

LPC-DHA/EPA-Enriched Diets Increase Brain DHA and Modulate Behavior in Mice That Express Human

Sarah B Scheinman, Dhavamani Sugasini, Monay Zayed, Poorna C R Yalagala, Felecia M Marottoli, Papasani V Subbaiah, Leon M Tai

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 32 citations in OpenAlex.

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  15. Review
  16. Potential role of hepatic lipase in the accretion of docosahexaenoic acid (DHA) by the brain.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2021
    Article
  17. The Role of Mfsd2a in Nervous System Diseases.Frontiers in neuroscience · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sarah B ScheinmanDepartment of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, IL, United States.
Dhavamani SugasiniDivision of Endocrinology and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, IL, United States.
Monay ZayedDepartment of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, IL, United States.
Poorna C R YalagalaDivision of Endocrinology and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, IL, United States.
Felecia M MarottoliDepartment of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, IL, United States.
Papasani V SubbaiahDivision of Endocrinology and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, IL, United States.
Leon M TaiDepartment of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, IL, United States.
University of Illinois Chicago · US

Funding

Deciphering molecular mechanisms that underlie brain endothelial cell dysfunction with APOE4R01AG061114 · NIA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Leon Maing Tai · 2019 to 2026
$4.7M
Improving cognition and enriching brain DHA in APOE4 mice through dietary LPC-DHAR21AG061715 · NIA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI TAI, LEON MAING · 2019 to 2020
$440k
NIA NIH HHS R01 AG061114NIA NIH HHS R21 AG061715
6 · The paper itself

Abstract

Compared with

Indexed as

agingAPOE4DHALPC-DHAmemory

Identifiers

PMID34276296
PMCPMC8282213
OpenAlexW3173831386

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.