ArticleClinical, cosmetic and investigational dermatology2021
The 10-Point Plan 2021: Updated Concepts for Improved Procedural Safety During Facial Filler Treatments.
Article in Clinical, cosmetic and investigational dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 39 citations in OpenAlex.
- Malar Edema after Hyaluronic Acid Dermal Fillers: Expert Recommendations on Etiology, Prevention, and Management.Dermatology and therapy · 2026Review
- LA VISIONAesthetic plastic surgery · 2026Article
- Guide for Managing Vascular Occlusion Due to Fillers with Extended Neuro-Ophthalmic Involvement: A Review of Diagnosis, Classification and Treatment.Aesthetic plastic surgery · 2026Review
- Minimally Invasive Aesthetic Treatments for the Corrective Patient Archetype: Transforming Lives.Aesthetic plastic surgery · 2026Review
- Effective Management of Late Inflammatory Nodules Following Hyaluronic Acid Fillers: A Case Series Treated With Methotrexate.Plastic and reconstructive surgery. Global open · 2026Article
- Vascular Occlusion Following Low-volume Chin Filler: Successful Management With High-dose Pulsed Hyaluronidase.Plastic and reconstructive surgery. Global open · 2026Article
- Severe anaphylactic shock suspectedly induced by injection of recombinant humanized type III collagen lyophilized fiber for facial skin improvement: a case report.Frontiers in allergy · 2026Article
- Facial Overfilled Syndrome: A Narrative Clinical Review.Clinical, cosmetic and investigational dermatology · 2026Review
- A Case of Orbital Cellulitis After Hyaluronic Acid Filler Injection: A Case Report.Journal of cosmetic dermatology · 2025Article
- Complications of Periorbital Cosmetic Hyaluronic Acid Filler Injections: A Major ReviewTurkish journal of ophthalmology · 2025Review
- Dermal Filler Use in Patients Undergoing Chemotherapy and Radiation Therapy.JMIR dermatology · 2025Review
- Integrating VYC-12L With Energy-Based Devices for Skin-Quality Improvement: Global Expert Considerations for Safe and Effective Outcomes.Journal of cosmetic dermatology · 2025Article
- Prevention and Management of Complications With a Hyaluronic Acid-Calcium Hydroxyapatite Hybrid Injectable.Clinical, cosmetic and investigational dermatology · 2025Review
- Structural Aesthetic Treatment With the Hyaluronic Acid Filler VYC-25L: Global Expert Considerations for Safe and Effective Long-Term Outcomes.Journal of cosmetic dermatology · 2025Article
- A Review: Causes, Consequences, and Management Strategies of Facial Overfilling.Clinical, cosmetic and investigational dermatology · 2025Review
- A Scoping Review of Hyaluronidase Use in Managing the Complications of Aesthetic Interventions.Aesthetic plastic surgery · 2024Article
- Choosing Juvéderm Volux™ to chin augmentation: Case report and flowchart for clinical evaluation.International journal of surgery case reports · 2024Article
- Cocaine Nose Correction: A Nonsurgical Approach Using a Novel Hyaluronic Acid Filler.Plastic and reconstructive surgery. Global open · 2023Article
- Hyaluronic Acid Fillers and ASIA Syndrome: Case Studies.Clinical, cosmetic and investigational dermatology · 2023Article
- HA PEGylated Filler in Association with an Infrared Energy Device for the Treatment of Facial Skin Aging: 150 Day Follow-Up Data Report.Pharmaceuticals (Basel, Switzerland) · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dermal filler treatments require constant reassessment for improving and safeguarding the rapidly evolving aesthetic field. Suboptimal injection technique, patient selection and product knowledge have touted a concerning increase in filler complications, with new challenges such as the COVID-19 pandemic leading to new paradigms in the understanding, prevention, diagnosis and treatment of complications. The updated 10-point plan has been developed to curtail complications through consideration of causative factors, categorized as patient, product, and procedure-related. Patient-related factors include a preprocedural consultation with careful elucidation of skin conditions (acne, rosacea, dermatitis), systemic disease (allergies, autoimmune disease, underlying bacterial and viral disease (herpes simplex virus, COVID-19 infection), medications (antineoplastic drugs, recreational drugs) and previous cosmetic procedures (including fillers and energy-based devices). Patient assessment should include standardized photography and also evaluate the role of social media, ethnicity, gender, generational, and LGBTQ+ needs. Specified informed consent for both adverse events and their treatment is essential due to the increase in vascular complications, including the risk of blindness. Product-related factors include the powerful advantage of reversibility when using hyaluronic acid (HA) products. Product characteristics such as molecular weight and filler degradation should be understood. Product layering over late or minimally degradable fillers is still inadvisable due to the initial filler being teased into reactivity. Procedural factors such as consistent photographic documentation, procedural planning, aseptic non-touch technique (ANTT), knowledge of topographical anatomy and angiosomes, and technical dexterity including pinch anatomy and needle skills are of pivotal importance. The final section is dedicated to algorithms and checklists for managing and treating complications such as allergic hypersensitivity reactions, vascular events, infection, edema and late-onset adverse events (LOAEs). The updated 10-point plan is a methodical strategy aimed at further minimising the risk of dermal filler complications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.