ArticleOncoTargets and therapy2021
Preoperative Serum Hypersensitive-c-Reactive-Protein (Hs-CRP) to Albumin Ratio Predicts Survival in Patients with Luminal B Subtype Breast Cancer.
Article in OncoTargets and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Role of the C-reactive protein-albumin ratio in predicting survival after breast cancer: A systematic review and meta-analysis.Pakistan journal of medical sciences · 2026Review
- Predictive value of postoperative C-reactive protein-to-albumin ratio for severe complications following radical gastrectomy in gastric cancer patients.Frontiers in medicine · 2026Article
- Inflammatory indices are associated with non-suicidal self-injury in adolescents with major depressive disorder.BMC psychiatry · 2025Article
- Associations of the C-reactive protein-albumin-lymphocyte index with all-cause and cardiovascular mortality among individuals with cardiovascular disease: evidence from the NHANES 2001-2010.BMC cardiovascular disorders · 2025Article
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- Influence of blood glucose fluctuations on chemotherapy efficacy and safety in type 2 diabetes mellitus patients complicated with lung carcinoma.World journal of diabetes · 2024Article
- The relationship between high-sensitivity C-reactive protein and gallstones: a cross-sectional analysis.Frontiers in medicine · 2024Article
- Serum Metabolic Characterization of Vitamin E Deficiency inAnimals : an open access journal from MDPI · 2023Article
- Prognostic value of preoperative immune-nutritional scoring systems in remnant gastric cancer patients undergoing surgery.World journal of gastrointestinal surgery · 2023Article
- Elevation of preoperative serum hs-CRP is an independent risk factor for malnutrition in patients with gastric cancer.Frontiers in oncology · 2023Article
- Adherence to Mediterranean Diet and Nutritional Status in Women with Breast Cancer: What Is Their Impact on Disease Progression and Recurrence-Free Patients' Survival?Current oncology (Toronto, Ont.) · 2022Article
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- Association between Pre-Existing Sleep Disorders and Survival Rates of Patients with Breast Cancer.Cancers · 2022Article
- Rosin Derivative IDOAMP Inhibits Prostate Cancer Growth via Activating RIPK1/RIPK3/MLKL Signaling Pathway.Oxidative medicine and cellular longevity · 2022Article
- Neutrophil-to-Lymphocyte Ratio Better Than High-Sensitivity C-Reactive Protein in Predicting Stroke-Associated Pneumonia in Afebrile Patients.Neuropsychiatric disease and treatment · 2021Article
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3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveTo evaluate the clinical prognostic significance of preoperative serum hypersensitive-c-reactive-protein (Hs-CRP) to albumin ratio (CAR) in patients with luminal B subtype breast cancer.
methodsA total of 199 patients with luminal B subtype breast cancer enrolled in this study were analyzed retrospectively. The optimal cutoff value of CAR was performed by the receiver operating characteristic curve (ROC). The associations between luminal B subtype breast cancer and clinicopathological variables by CAR were performed by chi-square test. Kaplan-Meier and log rank method were used for survival analysis. The independent prognostic factors were determined by univariate and multivariate Cox's proportional hazards regression model.
resultsThe patients were divided into low CAR group (CAR<0.044) and high CAR group (CAR≥0.044) by ROC. CAR was the independent factor by univariate and multivariate analysis, and the mean DFS and OS in the low CAR group survived longer than those in the high CAR group (p<0.05). According to the endocrine therapy with aromatase inhibitors, the mean survival time of DFS and OS in the low CAR group was significantly higher than that in the high CAR group (p<0.05). Moreover, patients with pathological I+II stage survived longer than those with pathological III stage, and the mean survival time of DFS and OS in the low CAR group was significantly higher than that in the high CAR group (p<0.05). Patients without lymph vessel invasion survived longer than those with lymph vessel invasion (p<0.05), and the mean survival time of DFS and OS in low the CAR group was significantly higher than that in the high CAR group (p<0.05).
conclusionPreoperative CAR was significantly associated with survival and prognosis of breast cancer, and it can be used as a routine prognostic indicator to predict the prognosis of luminal B subtype breast cancer.
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