Evidence map›Paper›PMID 34276195›Full record

ArticleAnnals of gastroenterology

Underwater endoscopic mucosal resection of adenomas and colorectal serrated lesions: a prospective clinical study.

Pedro Bothrel Nogueira, Walton Albuquerque, Ricardo Castejon Nascimento, Bruna Santos Marianelli, Frederico Fonseca Campos, Rodrigo Albuquerque Carreiro, Renata Figueiredo Rocha, Roberto Motta Pereira, Vitor Nunes Arantes

Abstract read
In one paragraph

Article in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pedro Bothrel NogueiraDepartment of Digestive Endoscopy, Hospital Madre Teresa (Pedro Bothrel Nogueira, Walton Albuquerque, Ricardo Castejon Nascimento, Bruna Santos Marianelli, Frederico Fonseca Campos, Rodrigo Albuquerque Carreiro, Renata Figueiredo Rocha, Roberto Motta Pereira).
Walton AlbuquerqueDepartment of Digestive Endoscopy, Hospital Madre Teresa (Pedro Bothrel Nogueira, Walton Albuquerque, Ricardo Castejon Nascimento, Bruna Santos Marianelli, Frederico Fonseca Campos, Rodrigo Albuquerque Carreiro, Renata Figueiredo Rocha, Roberto Motta Pereira).
Ricardo Castejon NascimentoDepartment of Digestive Endoscopy, Hospital Madre Teresa (Pedro Bothrel Nogueira, Walton Albuquerque, Ricardo Castejon Nascimento, Bruna Santos Marianelli, Frederico Fonseca Campos, Rodrigo Albuquerque Carreiro, Renata Figueiredo Rocha, Roberto Motta Pereira).
Bruna Santos MarianelliDepartment of Digestive Endoscopy, Hospital Madre Teresa (Pedro Bothrel Nogueira, Walton Albuquerque, Ricardo Castejon Nascimento, Bruna Santos Marianelli, Frederico Fonseca Campos, Rodrigo Albuquerque Carreiro, Renata Figueiredo Rocha, Roberto Motta Pereira).
Frederico Fonseca CamposDepartment of Digestive Endoscopy, Hospital Madre Teresa (Pedro Bothrel Nogueira, Walton Albuquerque, Ricardo Castejon Nascimento, Bruna Santos Marianelli, Frederico Fonseca Campos, Rodrigo Albuquerque Carreiro, Renata Figueiredo Rocha, Roberto Motta Pereira).
Rodrigo Albuquerque CarreiroDepartment of Digestive Endoscopy, Hospital Madre Teresa (Pedro Bothrel Nogueira, Walton Albuquerque, Ricardo Castejon Nascimento, Bruna Santos Marianelli, Frederico Fonseca Campos, Rodrigo Albuquerque Carreiro, Renata Figueiredo Rocha, Roberto Motta Pereira).
Renata Figueiredo RochaDepartment of Digestive Endoscopy, Hospital Madre Teresa (Pedro Bothrel Nogueira, Walton Albuquerque, Ricardo Castejon Nascimento, Bruna Santos Marianelli, Frederico Fonseca Campos, Rodrigo Albuquerque Carreiro, Renata Figueiredo Rocha, Roberto Motta Pereira).
Roberto Motta PereiraDepartment of Digestive Endoscopy, Hospital Madre Teresa (Pedro Bothrel Nogueira, Walton Albuquerque, Ricardo Castejon Nascimento, Bruna Santos Marianelli, Frederico Fonseca Campos, Rodrigo Albuquerque Carreiro, Renata Figueiredo Rocha, Roberto Motta Pereira).
Vitor Nunes ArantesFaculdade de Medicina da Universidade Federal de Minas Gerais, Alfa Institute of Gastroenterolgy (Vitor Nunes Arantes), Belo Horizonte, Minas Gerais, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUnderwater endoscopic mucosal resection (UEMR) without submucosal injection has been described as an alternative technique to the endoscopic resection of adenomas and colorectal serrated lesions. We aimed to assess the feasibility, safety, and efficacy of UEMR in a Brazilian setting.

methodsThis was a prospective observational study of consecutive patients who underwent UEMR between January and July 2019, in a single tertiary care center. Inclusion criteria were lesions without endoscopic stigmata of deep submucosal invasion in patients referred for endoscopic resection of colorectal adenomas, and serrated lesions detected in a previous colonoscopy. The following features were assessed: complete resection rate, en bloc resection rate, resection time, adverse events, and resection infeasibility.

resultsA total of 36 patients underwent UEMR for 51 colorectal lesions. The mean/median lesion size was 16.24/13 mm and the mean/median resection time was 16.97/9.19 min. Histopathology revealed the following: tubular adenoma (43.1%), tubulovillous adenoma (13.7%), serrated lesions (41.2%), and intramucosal adenocarcinoma (2%). Complete resection was achieved in 86.3% of cases; 52.9% of the lesions were removed en bloc, while 47.1% were resected in a piecemeal fashion. UEMR was feasible in 96.1% of cases and failed on 2 occasions, requiring conversion to standard endoscopic mucosal resection. Minor intraoperative bleeding occurred in 5 patients (9.8%) and only 1 presented with delayed bleeding (2%), all controlled endoscopically.

conclusionUEMR for removal of adenomas and colorectal serrated lesions was demonstrated to be feasible, safe and effective.

Indexed as

colonoscopycolorectal adenomascolorectal serrated lesionsUnderwater endoscopic mucosal resection

Identifiers

PMID34276195
PMCPMC8276360

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.