Evidence map›Paper›PMID 34276189›Full record

ArticleAnnals of gastroenterology

Combined approach for embolization of otherwise unmanageable gastric varices.

Anna Maria Ierardi, Aldo Carnevale, Giulia Tosetti, Mario D'Amico, Melchiore Giganti, Vincenzo La Mura, Cristian Bonelli, Matteo Renzulli, Pietro Lampertico, Massimo Primignani and 1 more

Abstract read
In one paragraph

Article in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Anna Maria IerardiRadiology Department, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan (Anna Maria Ierardi, Gianpaolo Carrafiello).
Aldo CarnevaleRadiology Department, University Radiology Unit, Sant'Anna University Hospital, Ferrara (Aldo Carnevale).
Giulia TosettiFoundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Division of Gastroenterology and Hepatology, CRC "A. M. and A. Migliavacca" Center for Liver Disease, Milan (Giulia Tosetti, Massimo Primignani).
Mario D'AmicoUOC Radiodiagnostica; Ospedali Riuniti Villa Sofia-Cervello, Palermo (Mario D'Amico).
Melchiore GigantiDepartment of Morphology, Surgery and Experimental Medicine, University of Ferrara (Melchiore Giganti).
Vincenzo La MuraFondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, U.O.C. Medicina Generale Emostasi e Trombosi, University of Milan (Vincenzo La Mura).
Cristian BonelliHealthcare Professionals Department, Foundation IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan (Cristian Bonelli).
Matteo RenzulliRadiology Unit, Department of Experimental, Diagnostic and Speciality Medicine, Sant'Orsola Hospital, University of Bologna (Matteo Renzulli).
Pietro LamperticoFoundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Division of Gastroenterology and Hepatology, CRC "A. M. and A. Migliavacca" Center for Liver Disease, Milan (Giulia Tosetti, Massimo Primignani).
Massimo PrimignaniFoundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Division of Gastroenterology and Hepatology, CRC "A. M. and A. Migliavacca" Center for Liver Disease, Milan (Giulia Tosetti, Massimo Primignani).
Gianpaolo CarrafielloRadiology Department, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan (Anna Maria Ierardi, Gianpaolo Carrafiello).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to determine the feasibility, safety and effectiveness of combined percutaneous transhepatic obliteration (PTO) and balloon-occluded retrograde transvenous obliteration (BRTO) therapy for the treatment of patients with high-risk bleeding gastric varices.

methodsTen patients were retrospectively reviewed. All the patients presented gastric varices, according to the Sarin classification, at high risk of bleeding, and not otherwise manageable. Patients with portal vein thrombosis were excluded. All patients were treated with a combination of PTO and BRTO. In all cases the gastric varices were embolized with glue, combined with coils or not, with an occlusion balloon inflated into the shunt. In 7 cases, embolization was immediate; in the remaining 3 the balloon remained inflated for 4 h and in 2 of them embolization of the shunt was required. Technical success was defined as complete obliteration of the gastric varices observed during a contrast-enhanced computed tomography study and endoscopy within 1 month following treatment. Clinical success was defined as absence of bleeding of gastric varices during the follow-up period. Major and minor complications during the follow up were recorded.

resultsTwelve sessions of combined PTO and BRTO procedures were performed in 10 patients; in 2 patients a new combined treatment was required during the follow up. Technical and clinical success was 100%. Neither major nor minor procedure-related complications were observed.

conclusionCombined PTO and BRTO therapy is safe and effective for the treatment of gastric varices that cannot be managed otherwise.

Indexed as

balloon-occluded retrograde transvenous obliterationgastric varicesGastrointestinal hemorrhagepercutaneous transhepatic obliterationportal hypertension

Identifiers

PMID34276189
PMCPMC8276367

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.