Evidence map›Paper›PMID 34276154›Full record

ArticleJournal of clinical and experimental hepatology

Liver Transplantation Society of India Guidelines for the Management of Acute Liver Injury Secondary to Yellow Phosphorus-Containing Rodenticide Poisoning Using the Modified Delphi Technique of Consensus Development.

Mettu S Reddy, Akila Rajakumar, Johns S Mathew, L Venkatakrishnan, Dinesh Jothimani, S Sudhindran, Mathew Jacob, Krishnasamy Narayanasamy, Radhika Venugopal, Ravi Mohanka and 14 more

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Acute liver failure and liver transplantation.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2025
    Review
  2. Liver support systems and liver transplantation in acute liver failure.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Review
  3. Prognostic markers in hepatitis A-related pediatric acute liver failure and validation of the Peds-hepatitis A virus prognostic model.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024
    Article
  4. Novel radiological technique to recognize acute liver failure caused by yellow phosphorous containing rodenticides.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023
    Article
  5. Review
  6. Low-Volume Plasma Exchange to Treat Children with Acute Liver Failure.Journal of clinical and experimental hepatology
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 10 institutions in 2 countries.

Mettu S ReddyInstitute of Liver Disease & Transplantation, Dr Rela Institute & Medical Center, Chennai, India.
Akila RajakumarDepartment of Liver Anesthesia & Intensive Care, Dr Rela Institute & Medical Center, Chennai, India.
Johns S MathewDepartment of Liver Transplantation & Gastrointestinal Surgery, Amrita Hospitals, Kochi, India.
L VenkatakrishnanDepartment of Gastroenterology, PSG Hospitals, Coimbatore, India.
Dinesh JothimaniDepartment of Hepatology, Dr Rela Institute & Medical Center, Chennai, India.
S SudhindranDepartment of Liver Transplantation & Gastrointestinal Surgery, Amrita Hospitals, Kochi, India.
Mathew JacobMultiorgan Transplantation & Hepatobiliary Surgery, Aster Medicity, Kochi, India.
Krishnasamy NarayanasamyDepartment of Hepatology, Madras Medical College, Chennai, India.
Radhika VenugopalDepartment of Hepatology, Dr Rela Institute & Medical Center, Chennai, India.
Ravi MohankaDepartment of Liver Transplantation & HPB Surgery, Global Hospital, Mumbai, India.
Ilankumaran KaliamoorthyDepartment of Liver Anesthesia & Intensive Care, Dr Rela Institute & Medical Center, Chennai, India.
Joy VargheseDepartment of Hepatology & Liver Transplantation, Gleneagles Global Hospital & Health City, Chennai, India.
Charles PanackelDepartment of Hepatology & Liver Transplantation, Aster Medicity, Kochi, India.
Zubair MohamedDepartment of Anesthesiology & Critical Care Medicine, Amrita Hospitals, Kochi, India.
Mukul VijDepartment of Pathology & Laboratory Medicine, Dr Rela Institute & Medical Center, Chennai, India.
Deepti SachanDepartment of Transfusion Medicine, Dr Rela Institute & Medical Center, Chennai, India.
V V PillayDepartment of Forensic Medicine & Toxicology, Amrita Hospitals, Kochi, India.
Sanjiv SaigalDepartment of Hepatology & Liver Transplantation, Medanta Medicity, Gurgaon, India.
Radhakrishna DhimanDepartment of Hepatology & Liver Transplantation, Post-graduate Institute of Medical Education & Research, Chandigarh, India.
Arvinder S SoinDepartment of Liver Transplantation & Regenerative Medicine, Medanta Medicity, Gurgaon, India.
Subhash GuptaCentre for Liver & Biliary Sciences, Max Super Specialty Hospital, Saket, Delhi, India.
Julia WendonInstitute of Liver Studies, Kings College Hospital, London, UK.
Mohamed RelaInstitute of Liver Disease & Transplantation, Dr Rela Institute & Medical Center, Chennai, India.
Shiv K SarinDepartment of Hepatology, Institute of Liver & Biliary Sciences, New Delhi, India.
Amrita Institute of Medical Sciences and Research Centre · INAster Medcity · INGlobal Hospitals · INMedanta The Medicity · INInstitute of Liver and Biliary Sciences · INKG Hospital · INKing's College Hospital · GBMadras Medical College · INMax Super Speciality Hospital · INPost Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute liver failure caused by the ingestion of yellow phosphorus-containing rodenticide has been increasing in incidence over the last decade and is a common indication for emergency liver transplantation in Southern and Western India and other countries. Clear guidelines for its management are necessary, given its unpredictable course, potential for rapid deterioration and variation in clinical practice.

methodsA modified Delphi approach was used for developing consensus guidelines under the aegis of the Liver Transplantation Society of India. A detailed review of the published literature was performed. Recommendations for three areas of clinical practice, assessment and initial management, intensive care unit (ICU) management and liver transplantation, were developed.

resultsThe expert panel consisted of 16 clinicians, 3 nonclinical specialists and 5 senior advisory members from 11 centres. Thirty-one recommendations with regard to criteria for hospital admission and discharge, role of medical therapies, ICU management, evidence for extracorporeal therapies such as renal replacement therapy and therapeutic plasma exchange, early predictors of need for liver transplantation and perioperative care were developed based on published evidence and combined clinical experience.

conclusionDevelopment of these guidelines should help standardise care for patients with yellow phosphorus poisoning and identify areas for collaborative research.

Indexed as

acute liver failureALF, acute liver failureALI, acute liver injuryconsensus guidelinesDDLT, deceased donor liver transplantationICU, intensive care unitINR, international normalised ratioKCC, Kings College CriteriaLDLT, living donor liver transplantationliver transplantationLT, liver transplantationLTSI, Liver Transplantation Society of IndiaMELD, model for end-stage liver diseaserat killer poisonRRT, renal replacement therapyTPE, therapeutic plasma exchangeyellow phosphorusYP, yellow phosphorus

Identifiers

PMID34276154
PMCPMC8267358
OpenAlexW3091812562

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.