Evidence map›Paper›PMID 34275989›Full record

ArticleAnnals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia2022

Thymoma-Related Stiff-Person Syndrome with Successfully Treated by Surgery.

Akihiro Sasaki, Tatsuya Kato, Hideki Ujiie, Satoru Wakasa, Setsuyuki Otake, Keisuke Kikuchi, Koichi Ohno

Open access · goldAbstract readCase Reports
In one paragraph

Article in Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Myasthenia Gravis and Thymoma.Muscle & nerve · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Stiff-Person Syndrome Associated With Metastatic Thymoma.Journal of clinical neurology (Seoul, Korea) · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Akihiro SasakiDepartment of Surgery, Obihiro Kosei General Hospital, Obihiro, Hokkaido, Japan.
Tatsuya KatoDepartment of Cardiovascular and Thoracic Surgery, Hokkaido University Faculty and School of Medicine, Sapporo, Hokkaido, Japan.
Hideki UjiieDepartment of Cardiovascular and Thoracic Surgery, Hokkaido University Faculty and School of Medicine, Sapporo, Hokkaido, Japan.
Satoru WakasaDepartment of Cardiovascular and Thoracic Surgery, Hokkaido University Faculty and School of Medicine, Sapporo, Hokkaido, Japan.
Setsuyuki OtakeDepartment of Surgery, Obihiro Kosei General Hospital, Obihiro, Hokkaido, Japan.
Keisuke KikuchiDepartment of Pathology, Obihiro Kosei General Hospital, Obihiro, Hokkaido, Japan.
Koichi OhnoDepartment of Surgery, Obihiro Kosei General Hospital, Obihiro, Hokkaido, Japan.
Hokkaido University · JPObihiro Kosei General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionStiff-person syndrome (SPS) is a rare autoimmune neurological disorder. Paraneoplastic SPS associated with malignant tumors such as thymoma occurs in approximately 5% of all SPS cases. We present a rare case of thymoma accompanied by SPS successfully treated using surgery. PRESENTATION OF CASE: A 26-year-old woman presented with lower limbs convulsions and gait disturbance and complained of leg pain. Cerebrospinal fluid and blood test results showed a high level of anti-glutamic acid decarboxylase (GAD) antibodies. Computed tomography showed anterior mediastinal tumor suggestive of a thymoma. She underwent extended thymectomy, and her symptoms gradually improved after surgery. No evidence of recurrent thymoma and SPS has been observed over 44 months.

conclusionSurgical treatment would be effective for patients with SPS and thymoma.

Indexed as

Stiff-Person SyndromeThymomaThymus NeoplasmsAdultFemaleHumansNeoplasm Recurrence, LocalTreatment Outcomeanti-acetylcholine receptor antibodymyasthenia gravisparaneoplastic stiff-person syndromestiff-person syndromethymoma

Identifiers

PMID34275989
PMCPMC9763711
OpenAlexW3184726837

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.