Evidence map›Paper›PMID 34275932›Full record

ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2021

Significance of LINC00460 in the progression and prognosis in digestive tract tumors.

Xiaoyan Lin, Bo Zhou, Jun Ma

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 62% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Xiaoyan LinMedical Research Center, Second Affiliated Hospital, Zhengzhou University, Zhengzhou 450014, China. xiaoyanlin2020@163.com.
Bo ZhouMedical Research Center, Second Affiliated Hospital, Zhengzhou University, Zhengzhou 450014, China.
Jun MaMedical Research Center, Second Affiliated Hospital, Zhengzhou University, Zhengzhou 450014, China. majun@zzu.edu.cn.
Second Affiliated Hospital of Zhengzhou University · CN

Funding

the Key Medical Science and Technique Foundation of Health Commission of Henan Province SB201901113 and LHGJ20190303the Special Research & Development and Promotion Projects of Science and Technology Agency in Henan Province 192102310048
6 · The paper itself

Abstract

The long intergic non-protein coding RNA 460 (LINC00460) is abnormally highly expressed in gastrointestinal tumors and plays an important role in promoting tumor formation and development. LINC00460 is mainly distributed in cytoplasm and has many abnormal gene variants of single nucleotide polymorphism in tumors. LINC00460 can promote the proliferation, metastasis, angiogenesis, radiotherapy and chemotherapy resistance, inhibit the apoptosis of tumor cells, and further promote the malignant progression of tumors via involving in chromatin state maintenance, methylation modification, endogenous competition and transcriptional regulation. It may serve as a valuable tumor marker and therapeutic target.

Indexed as

Gastrointestinal NeoplasmsRNA, Long NoncodingCell Line, TumorCell MovementCell ProliferationGene Expression Regulation, NeoplasticHumansPrognosisRNA, Long Noncodinggastrointestinal tumorslong intergic non-protein coding RNA 460tumor promoter

Identifiers

PMID34275932
PMCPMC10930199
OpenAlexW3185328583

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.