Evidence map›Paper›PMID 34275870›Full record

Trial reportBMJ global health2021

Relative efficiency of demand creation strategies to increase voluntary medical male circumcision uptake: a study conducted as part of a randomised controlled trial in Zimbabwe.

Collin Mangenah, Webster Mavhu, Diego Cerecero Garcia, Chiedza Gavi, Polite Mleya, Progress Chiwawa, Sandra Chidawanyika, Getrude Ncube, Sinokuthemba Xaba, Owen Mugurungi and 8 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ global health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 4 countries.

Collin MangenahCentre for Sexual Health and HIV/AIDS Research Zimbabwe, Harare, Zimbabwe cmangenah1@gmail.com.ORCID 0000-0002-0733-0622
Webster MavhuCentre for Sexual Health and HIV/AIDS Research Zimbabwe, Harare, Zimbabwe.ORCID 0000-0003-1881-4398
Diego Cerecero GarciaDivision of Health Economics and Health Systems Innovations, Instituto Nacional de Salud Publica, Cuernavaca, Mexico.
Chiedza GaviCentre for Sexual Health and HIV/AIDS Research Zimbabwe, Harare, Zimbabwe.
Polite MleyaCentre for Sexual Health and HIV/AIDS Research Zimbabwe, Harare, Zimbabwe.
Progress ChiwawaCentre for Sexual Health and HIV/AIDS Research Zimbabwe, Harare, Zimbabwe.
Sandra ChidawanyikaCentre for Sexual Health and HIV/AIDS Research Zimbabwe, Harare, Zimbabwe.
Getrude NcubeMinistry of Health and Child Care, Harare, Zimbabwe.
Sinokuthemba XabaMinistry of Health and Child Care, Harare, Zimbabwe.
Owen MugurungiMinistry of Health and Child Care, Harare, Zimbabwe.
Noah TaruberekeraPopulation Services International Zimbabwe, Harare, Zimbabwe.
Ngonidzashe MadidiAdvance Program, IAVI, Nairobi, Kenya.
Katherine L FieldingFaculty of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK.
Cheryl JohnsonHIV Department, Geneva, Switzerland.
Karin HatzoldPopulation Services International, Washington, District of Columbia, USA.
Fern Terris-PrestholtFaculty of Public Health and Policy, London School of Hygiene & Tropical Medicine, London, UK.
Frances M CowanCentre for Sexual Health and HIV/AIDS Research Zimbabwe, Harare, Zimbabwe.
Sergio Bautista-ArredondoDivision of Health Economics and Health Systems Innovations, Instituto Nacional de Salud Publica, Cuernavaca, Mexico.
Centre for Sexual Health and HIV AIDS Research · ZWLiverpool School of Tropical Medicine · GBMinistry of Health and Child Welfare · ZWInstituto Nacional de Salud Pública · MXLondon School of Hygiene & Tropical Medicine · GBPopulation Services International · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSupply and demand-side factors continue to undermine voluntary medical male circumcision (VMMC) uptake. We assessed relative economic costs of four VMMC demand creation/service-delivery modalities as part of a randomised controlled trial in Zimbabwe.

methodsInterpersonal communication agents were trained and incentivised to generate VMMC demand across five districts using four demand creation modalities (standard demand creation (SDC), demand creation plus offer of HIV self-testing (HIVST), human-centred design (HCD)-informed approach, HCD-informed demand creation approach plus offer of HIVST). Annual provider financial expenditure analysis and activity-based-costing including time-and-motion analysis across 15 purposively selected sites accounted for financial expenditures and donated inputs from other programmes and funders. Sites represented three models of VMMC service-delivery: static (fixed) model offering VMMC continuously to walk-in clients at district hospitals and serving as a district hub for integrated mobile and outreach services, (2) integrated (mobile) modelwhere staff move from the district static (fixed) site with their commodities to supplement existing services or to recently capacitated health facilities, intermittently and (3) mobile/outreach model offering VMMC through mobile clinic services in more remote sites.

resultsTotal programme cost was $752 585 including VMMC service-delivery costs and average cost per client reached and cost per circumcision were $58 and $174, respectively. Highest costs per client reached were in the HCD arm-$68 and lowest costs in standard demand creation ($52) and HIVST ($55) arms, respectively. Highest cost per client circumcised was observed in the arm where HIVST and HCD were combined ($226) and the lowest in the HCD alone arm ($160). Across the three VMMC service-delivery models, unit cost was lowest in static (fixed) model ($54) and highest in integrated mobile model ($63). Overall, economies of scale were evident with unit costs lower in sites with higher numbers of clients reached and circumcised.

conclusionsThere was high variability in unit costs across arms and sites suggesting opportunities for cost reductions. Highest costs were observed in the HCD+HIVST arm when combined with an integrated service-delivery setting. Mobilisation programmes that intensively target higher conversion rates as exhibited in the SDC and HCD arms provide greater scope for efficiency by spreading costs. TRIAL REGISTRATION NUMBER: PACTR201804003064160.

Indexed as

Circumcision, MaleHIV InfectionsHumansMaleZimbabwehealth economicsHIVprevention strategiespublic healthrandomised control trial

Identifiers

PMID34275870
PMCPMC8287601
OpenAlexW3183744890

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.