Evidence map›Paper›PMID 34275728›Full record

ArticleTrends in parasitology2021

The best sugar in town for malaria transmission.

Medard Ernest, Thiago Luiz Alves E Silva, Joel Vega-Rodríguez

Open access · greenAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Trends in parasitology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Role of microbiota in host-Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Medard ErnestLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA.
Thiago Luiz Alves E SilvaLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA.
Joel Vega-RodríguezLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA. Electronic address: joel.vega-rodriguez@nih.gov.
National Institutes of Health · US

Funding

Host-parasite-vector interactions during malaria transmissionZIAAI001250 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI VEGA-RODRIGUEZ, JOEL · 2019 to 2025
$9.9M
Intramural NIH HHS ZIA AI001250
6 · The paper itself

Abstract

Anopheles mosquitoes feed on plant nectars as their main source of sugar. Wang et al. show that Asaia bacteria proliferate in the midgut of mosquitoes that feed on glucose or trehalose. Asaia increases the lumenal pH by downregulating mosquito vacuolar ATPase expression, therefore increasing Plasmodium gametogenesis and vector competence.

Indexed as

AnophelesMalariaPlasmodiumAnimalsMosquito VectorsSugarsSugarsAnophelesglucosemicrobiomePlasmodiumvectorial capacity

Identifiers

PMID34275728
PMCPMC11022271
OpenAlexW3179776163

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.