Evidence map›Paper›PMID 34275477›Full record

ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2021

Fick versus flow: a real-time invasive cardiovascular magnetic resonance (iCMR) reproducibility study.

Yousef Arar, Tarique Hussain, Riad Abou Zahr, Vasu Gooty, Joshua S Greer, Rong Huang, Jennifer Hernandez, Jamie King, Gerald Greil, Surendranath R Veeram Reddy

Abstract read
In one paragraph

Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Interventional cardiovascular magnetic resonance: state-of-the-art.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Review
  9. Article
  10. Improved catheter tracking during cardiovascular magnetic resonance-guided cardiac catheterization using overlay visualization.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2022
    Article
  11. Review
  12. Review
  13. Direct assessment of total cavopulmonary connection power loss with interventional cardiac magnetic resonance in Fontan circulation.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yousef ArarDepartment of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA. Yousef.Arar@UTSouthwestern.edu.ORCID 0000-0002-9462-9947
Tarique HussainDepartment of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Riad Abou ZahrDepartment of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Vasu GootyDepartment of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Joshua S GreerDepartment of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Rong HuangResearch Administration, Children's Medical Center, Dallas, TX, USA.
Jennifer HernandezAnesthesiology and Pain Management, Children's Medical Center, Dallas, TX, USA.
Jamie KingDepartment of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Gerald GreilDepartment of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Surendranath R Veeram ReddyDepartment of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiac catheterization and cardiovascular magnetic resonance (CMR) imaging have distinct diagnostic roles in the congenital heart disease (CHD) population. Invasive CMR (iCMR) allows for a more thorough assessment of cardiac hemodynamics at the same time under the same conditions. It is assumed but not proven that iCMR gives an incremental value by providing more accurate flow quantification.

methodsSubjects with CHD underwent real-time 1.5 T iCMR using a passive catheter tracking technique with partial saturation pulse of 40° to visualize the gadolinium-filled balloon, CMR-conditional guidewire, and cardiac structures simultaneously to aid in completion of right (RHC) and left heart catheterization (LHC). Repeat iCMR and catheterization measurements were performed to compare reliability by the Pearson (PCC) and concordance correlation coefficients (CCC).

resultsThirty CHD (20 single ventricle and 10 bi-ventricular) subjects with a median age and weight of 8.3 years (2-33) and 27.7 kg (9.2-80), respectively,  successfully underwent iCMR RHC and LHC. No catheter related complications were encountered. Time taken for first pass RHC and LHC/aortic pull back was 5.1, and 2.9 min, respectively. Total success rate to obtain required data points to complete Fick principle calculations for all patients was 321/328 (98%). One patient with multiple shunts was an outlier and excluded from further analysis. The PCC for catheter-derived pulmonary blood flow (Qp) (0.89, p < 0.001) is slightly lower than iCMR-derived Qp (0.96, p < 0.001), whereas catheter-derived systemic blood flow (Qs) (0.62, p = < 0.001) was considerably lower than iCMR-derived Qs (0.94, p < 0.001). CCC agreement for Qp at baseline (C1-CCC = 0.65, 95% CI 0.41-0.81) and retested conditions (C2-CCC = 0.78, 95% CI 0.58-0.89) were better than for Qs at baseline (C1-CCC = 0.22, 95% CI - 0.15-0.53) and retested conditions (C2-CCC = 0.52, 95% CI 0.17-0.76).

conclusionThis study further validates hemodynamic measurements obtained via iCMR. iCMR-derived flows have considerably higher test-retest reliability for Qs. iCMR evaluations allow for more reproducible hemodynamic assessments in the CHD population.

Indexed as

Magnetic Resonance ImagingPulmonary CirculationCardiac CatheterizationHumansMagnetic Resonance SpectroscopyPredictive Value of TestsReproducibility of ResultsCardiac catheterizationCongenital heart diseaseDevice trackingInterventional CMRMagnetic resonance imagingReproducibility

Identifiers

PMID34275477
PMCPMC8287667

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.