Evidence map›Paper›PMID 34275334›Full record

ArticleHypertension (Dallas, Tex. : 1979)2021

Influence of Maternal Lifestyle and Diet on Perinatal DNA Methylation Signatures Associated With Childhood Arterial Stiffness at 8 to 9 Years.

Robert Murray, Negusse Kitaba, Elie Antoun, Philip Titcombe, Sheila Barton, Cyrus Cooper, Hazel M Inskip, Graham C Burdge, Pamela A Mahon, John Deanfield and 8 more

Open access · hybridAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

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  5. Cardiovascular Health Starts in the Womb.Hypertension (Dallas, Tex. : 1979) · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 3 countries.

Robert MurrayFrom the School of Human Development and Health, Institute of Developmental Sciences Building, Faculty of Medicine (R.M., N.K., E.A., G.C.B., K.M.G., M.A.H.), University of Southampton, United Kingdom.
Negusse KitabaFrom the School of Human Development and Health, Institute of Developmental Sciences Building, Faculty of Medicine (R.M., N.K., E.A., G.C.B., K.M.G., M.A.H.), University of Southampton, United Kingdom.
Elie AntounFrom the School of Human Development and Health, Institute of Developmental Sciences Building, Faculty of Medicine (R.M., N.K., E.A., G.C.B., K.M.G., M.A.H.), University of Southampton, United Kingdom.
Philip TitcombeMRC Lifecourse Epidemiology Unit (P.T., S.B., C.C., H.M.I., P.A.M., K.M.G.), University of Southampton, United Kingdom.
Sheila BartonMRC Lifecourse Epidemiology Unit (P.T., S.B., C.C., H.M.I., P.A.M., K.M.G.), University of Southampton, United Kingdom.
Cyrus CooperMRC Lifecourse Epidemiology Unit (P.T., S.B., C.C., H.M.I., P.A.M., K.M.G.), University of Southampton, United Kingdom.
Hazel M InskipMRC Lifecourse Epidemiology Unit (P.T., S.B., C.C., H.M.I., P.A.M., K.M.G.), University of Southampton, United Kingdom.
Graham C BurdgeFrom the School of Human Development and Health, Institute of Developmental Sciences Building, Faculty of Medicine (R.M., N.K., E.A., G.C.B., K.M.G., M.A.H.), University of Southampton, United Kingdom.
Pamela A MahonMRC Lifecourse Epidemiology Unit (P.T., S.B., C.C., H.M.I., P.A.M., K.M.G.), University of Southampton, United Kingdom.
John DeanfieldInstitute of Cardiovascular Sciences, University College London, United Kingdom (J.D.).
Julian P HalcoxSwansea University Medical School, Swansea University, United Kingdom (J.P.H., E.A.E.).
Elizabeth A EllinsSwansea University Medical School, Swansea University, United Kingdom (J.P.H., E.A.E.).
Jennifer BryantDepartment of Cardiac Magnetic Resonance Imaging, National Heart Centre Singapore (J.B.).
Charles PeeblesWessex Cardiothoracic Centre, Southampton University Hospitals NHS Trust, United Kingdom (C.P.).
Karen LillycropCentre for Biological Sciences, Faculty of Natural and Environmental Sciences (E.A., K.L.), University of Southampton, United Kingdom.
Keith M GodfreyFrom the School of Human Development and Health, Institute of Developmental Sciences Building, Faculty of Medicine (R.M., N.K., E.A., G.C.B., K.M.G., M.A.H.), University of Southampton, United Kingdom.
Mark A HansonFrom the School of Human Development and Health, Institute of Developmental Sciences Building, Faculty of Medicine (R.M., N.K., E.A., G.C.B., K.M.G., M.A.H.), University of Southampton, United Kingdom.
EpiGen Consortium
MRC Lifecourse Epidemiology Unit · GBUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Southampton · GBSwansea University · GBEssex Cardiothoracic Centre · GBNational Heart Centre Singapore · SGSt. John's College of Nursing · US

Funding

British Heart Foundation RG/15/17/31749Medical Research Council G0400491Medical Research Council G0601019Medical Research Council MC_PC_21000Medical Research Council MC_PC_21001Medical Research Council MC_PC_21003Medical Research Council MC_U147585819Medical Research Council MC_U147585824Medical Research Council MC_U147585827Medical Research Council MC_UP_A620_1014Medical Research Council MC_UP_A620_1015Medical Research Council MC_UU_12011/1Medical Research Council MC_UU_12011/2Medical Research Council MC_UU_12011/4Medical Research Council MR/J000094/1Versus Arthritis 17702Versus Arthritis 21231
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

DNA MethylationChildDietFemaleHumansLife StyleMagnetic Resonance ImagingMalePregnancyPrenatal Exposure Delayed EffectsPulse Wave AnalysisVascular Stiffnessaortablood pressureDNA methylationepigenomegenetic variation

Identifiers

PMID34275334
PMCPMC8357051
OpenAlexW3176763698

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.