Evidence map›Paper›PMID 34275188›Full record

SynthesisStress and health : journal of the International Society for the Investigation of Stress2022

The effects of school-based interventions on physiological stress in adolescents: A meta-analysis.

Amanda W G van Loon, Hanneke E Creemers, Ana Okorn, Simone Vogelaar, Anne C Miers, Nadira Saab, P Michiel Westenberg, Jessica J Asscher

Registry-linked trialOpen access · hybridAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Stress and health : journal of the International Society for the Investigation of Stress, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07173608 (Transforming Adolescent Perception and Mental Health Through Meditation and Cognitive Reappraisal A Mixed Method Study), which is not on this map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07173608 narecruitingnot on this mapstarted 2026, after this paper: background citation

Transforming Adolescent Perception and Mental Health Through Meditation and Cognitive Reappraisal A Mixed Method Study

TypeinterventionalSponsorBeth Israel Deaconess Medical CenterRan2026 to 2028Enrolled96ConditionsMeditation, Cognitive Reappraisal, Emotional RegulationArmsInner Engineering Program
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. The effects of school-based interventions on physiological stress in adolescents: A meta-analysis.Stress and health : journal of the International Society for the Investigation of Stress · 2022
    Pooled it
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Amanda W G van LoonDepartment of Child and Adolescent Studies, Utrecht University, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0001-6843-4102
Hanneke E CreemersForensic Child and Youth Care Sciences, University of Amsterdam, Amsterdam, The Netherlands.
Ana OkornDepartment of Child and Adolescent Studies, Utrecht University, Utrecht, The Netherlands.
Simone VogelaarDevelopmental and Educational Psychology, Leiden University, Leiden, The Netherlands.
Anne C MiersDevelopmental and Educational Psychology, Leiden University, Leiden, The Netherlands.
Nadira SaabGraduate School of Teaching (ICLON), Leiden University, Leiden, The Netherlands.
P Michiel WestenbergDevelopmental and Educational Psychology, Leiden University, Leiden, The Netherlands.
Jessica J AsscherDepartment of Child and Adolescent Studies, Utrecht University, Utrecht, The Netherlands.
Leiden University · NLUtrecht University · NLAmsterdam University of Applied Sciences · NLRadboud University Nijmegen · NL

Funding

Nederlandse Organisatie voor Wetenschappelijk Onderzoek 400.17.601Nederlandse Organisatie voor Wetenschappelijk Onderzoek 400.17.601, work package 3
6 · The paper itself

Abstract

Chronic stress is associated with dysregulations in the physiological stress system, resulting in diverse negative developmental outcomes. Since adolescence is a period characterized by increased stress-sensitivity, and schools are an important environment for the developing adolescent, school-based interventions promoting psychosocial functioning are of particular interest to prevent adverse outcomes. The present study therefore aimed to investigate the effectiveness of such interventions on hypothalamic pituitary adrenal-axis (i.e., cortisol) and cardiovascular (i.e., blood pressure [BP] and heart rate [HR]/heart rate variability [HRV]) parameters of stress in adolescents, and examined moderators of effectiveness. The search resulted in the inclusion of k = 9 studies for cortisol, k = 16 studies for BP, and k = 20 studies for HR/HRV. The results indicated a significant small overall effect on reducing BP, but no significant effect for HR/HRV. For cortisol, large methodological variation in the few primary studies did not allow for quantitative analyses, but a qualitative review demonstrated inconsistent results. For BP and HR/HRV, larger effects were observed for intervention programs with a mindfulness and/or meditation component, for interventions without a cognitive-behavioural component and for interventions with a higher intensity. Providing adolescents with techniques to improve indicators of physiological stress may prevent emerging mental health problems.

Indexed as

MeditationMindfulnessAdolescentHumansHydrocortisoneSchoolsStress, PhysiologicalHydrocortisoneadolescentsmeta-analysisphysiological stressschool-based intervention programs

Identifiers

PMID34275188
PMCPMC9291930
OpenAlexW3183817661

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.