Evidence map›Paper›PMID 34275108›Full record

ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2021

Circulating non-coding RNAs as new biomarkers and novel therapeutic targets in colorectal cancer.

L Yang, X Zhang, G Hu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

L YangNingbo University School of Medicine, Ningbo, 315211, China.
X ZhangThe Affiliated Hospital of Medical School, Ningbo University, Ningbo, 315020, China. zxj14@163.com.ORCID http://orcid.org/0000-0001-8795-551X
G HuThe Affiliated Hospital of Medical School, Ningbo University, Ningbo, 315020, China.
Ningbo University · CN

Funding

the Natural Science Foundation of Ningbo No.2016A610121
6 · The paper itself

Abstract

Colorectal cancer (CRC) is one of the most common malignant tumors, and a large number of patients are diagnosed and die every year. Due to the lack of appropriate diagnosis, prediction and treatment, early diagnosis rate of CRC is low and the prognosis is poor. Studies have found that abnormally expressed non-coding RNAs (ncRNAs) (including microRNAs (miRNAs), circular RNAs (circRNAs) and long non-coding RNAs (lncRNAs),etc.) play an important regulatory role in the occurrence and development of CRC. Some studies have shown that they are stable in the blood and can be detected repeatedly. They are expected to be non-invasive biomarkers for early diagnosis, prognosis evaluation, and prediction of drug sensitivity of CRC, as well as potential applications in the treatment of CRC.

Indexed as

Biomarkers, TumorColorectal NeoplasmsEarly Detection of CancerHumansMicroRNAsPrognosisRNA, CircularRNA, Long NoncodingRNA, UntranslatedBiomarkers, TumorMicroRNAsRNA, CircularRNA, Long NoncodingRNA, UntranslatedBiomarkersCirculating ncRNAsColorectal cancerDiagnosisPredictivePrognosisTherapeutic targets

Identifiers

PMID34275108
OpenAlexW3186385260

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.