SynthesisEuropean journal of epidemiology2021
Marital status and prostate cancer incidence: a pooled analysis of 12 case-control studies from the PRACTICAL consortium.
Synthesis in European journal of epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- 2022 Update on Prostate Cancer Epidemiology and Risk Factors-A Systematic Review.European urology · 2023Pooled it
- Marital status and perceived stress in men with advanced prostate cancer: A randomized-controlled trial of cognitive behavioral stress management.Journal of psychosomatic research · 2023Trial
- A novel prognostic nomogram for elderly renal cell carcinoma patients with lung metastases.Scientific reports · 2026Article
- Unravelling prostate cancer risk and protective factors among urology patients in a Tanzanian population.Frontiers in oncology · 2026Article
- Risk of aggressive prostate cancer with successive generations in the US among Latino men.Journal of the National Cancer Institute · 2025Article
- Shifting Marital Landscapes: Non-marriage and Its Public Health Implications in China, South Korea, and Japan.Journal of community health · 2025Article
- Prostate cancer screening: Knowledge, attitudes and practices in a sample of men in Ramotswa, Botswana.Journal of public health research · 2025Article
- Quantifying Suicide Risk in Prostate Cancer: A SEER-Based Predictive Model.Journal of epidemiology and global health · 2025Article
- Association of marital status with DNA methylation-based biological age among US older adults.Frontiers in public health · 2025Article
- A nomogram for predicting cancer-specific survival in patients with locally advanced unresectable esophageal cancer: development and validation study.Frontiers in immunology · 2025Article
- Prostate-specific antigen testing in the United States during 2008-2022 in relation to the US preventive services task force recommendations.Scientific reports · 2024Article
- Association and causal mediation between marital status and depression in seven countries.Nature human behaviour · 2024Article
- Gaps in the usage and reporting of multiple imputation for incomplete data: findings from a scoping review of observational studies addressing causal questions.BMC medical research methodology · 2024Article
- Explainable machine learning predicts survival of retroperitoneal liposarcoma: A study based on the SEER database and external validation in China.Cancer medicine · 2024Article
- The impact of marital status on tumor aggressiveness, treatment, and screening among black and white men diagnosed with prostate cancer.Cancer causes & control : CCC · 2024Article
- Survival benefit of combined immunotherapy and chemoradiotherapy in locally advanced unresectable esophageal cancer: an analysis based on the SEER database.Frontiers in immunology · 2024Article
- Marital Status Is a Prognostic Factor for Cardiovascular Mortality but Not a Prognostic Factor for Cancer Mortality in Siewert Type II Adenocarcinoma of the Esophagogastric Junction.Gastroenterology research · 2023Article
- Neighbourhood social deprivation and risk of prostate cancer.British journal of cancer · 2023Article
- Investigating the Anti-inflammatory Effect of Allopurinol on the Prevention of Prostate Cancer.Cureus · 2023Article
- The profile of Black South African men diagnosed with prostate cancer in the Free State, South Africa.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2023Article
Corrections and comments
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Authors and funding
29 authors at 17 institutions in 8 countries.
Funding
Abstract
While being in a committed relationship is associated with a better prostate cancer prognosis, little is known about how marital status relates to its incidence. Social support provided by marriage/relationship could promote a healthy lifestyle and an increased healthcare seeking behavior. We investigated the association between marital status and prostate cancer risk using data from the PRACTICAL Consortium. Pooled analyses were conducted combining 12 case-control studies based on histologically-confirmed incident prostate cancers and controls with information on marital status prior to diagnosis/interview. Marital status was categorized as married/partner, separated/divorced, single, or widowed. Tumours with Gleason scores ≥ 8 defined high-grade cancers, and low-grade otherwise. NCI-SEER's summary stages (local, regional, distant) indicated the extent of the cancer. Logistic regression was used to derive odds ratios (ORs) and 95% confidence intervals (CI) for the association between marital status and prostate cancer risk, adjusting for potential confounders. Overall, 14,760 cases and 12,019 controls contributed to analyses. Compared to men who were married/with a partner, widowed men had an OR of 1.19 (95% CI 1.03-1.35) of prostate cancer, with little difference between low- and high-grade tumours. Risk estimates among widowers were 1.14 (95% CI 0.97-1.34) for local, 1.53 (95% CI 1.22-1.92) for regional, and 1.56 (95% CI 1.05-2.32) for distant stage tumours. Single men had elevated risks of high-grade cancers. Our findings highlight elevated risks of incident prostate cancer among widowers, more often characterized by tumours that had spread beyond the prostate at the time of diagnosis. Social support interventions and closer medical follow-up in this sub-population are warranted.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.