Evidence map›Paper›PMID 34274187›Full record

ArticleAnais brasileiros de dermatologia

Successful treatment of diffuse cutaneous leishmaniasis caused by Leishmania amazonensis.

Raimunda Nonata Ribeiro Sampaio, Marina Freitas Ferreira, Sofia Sales Martins, Jorgeth de Oliveira Carneiro da Motta

Open access · goldAbstract readCase Reports
In one paragraph

Article in Anais brasileiros de dermatologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Leishmaniasis Incidence andPathogens (Basel, Switzerland) · 2026
    Article
  2. Review
  3. An Update on Clinical and Pathogenic Spectra of Leishmaniasis.Expert reviews in molecular medicine · 2025
    Review
  4. Article
  5. Humoral response in Leishmaniasis.Frontiers in cellular and infection microbiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Raimunda Nonata Ribeiro SampaioHospital Universitário de Brasília, Universidade de Brasília, Brasília, DF, Brazil. Electronic address: rnrsampaio@hotmail.com.
Marina Freitas FerreiraHospital Universitário de Brasília, Universidade de Brasília, Brasília, DF, Brazil.
Sofia Sales MartinsHospital Universitário de Brasília, Universidade de Brasília, Brasília, DF, Brazil.
Jorgeth de Oliveira Carneiro da MottaHospital Universitário de Brasília, Universidade de Brasília, Brasília, DF, Brazil.
Universidade de Brasília · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffuse cutaneous leishmaniasis is a rare universal disease associated with an inadequate host cell immune response, caused by different species: infantum, aethiopica, major, mexicana, and others, which presents the challenge of a poor therapeutic response. In Brazil, it is caused by L. amazonensis. A case confirmed by histopathology with an abundance of vacuolated macrophages full of amastigotes and lymphocyte scarcity, identified by RFLP-ITS1PCR and in vitro decrease and exhaustion of the host cell immune response to L. amazonensis antigen, was treated early (3 months after the onset) with Glucantime (2 months) and allopurinol (29 months) with clinical cure, after a follow-up for 30 months after treatment.

Indexed as

Antiprotozoal AgentsLeishmania mexicanaLeishmaniasis, CutaneousLeishmaniasis, Diffuse CutaneousBrazilHumansMeglumine AntimoniateAntiprotozoal AgentsMeglumine AntimoniateAllopurinolAntimonyDiffuse cutaneous leishmaniasisRecurrenceTherapy

Identifiers

PMID34274187
PMCPMC8441499
OpenAlexW3185092383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.