ArticleBiological psychiatry. Cognitive neuroscience and neuroimaging2022
Early Childhood Socioeconomic Status and Cognitive and Adaptive Outcomes at the Transition to Adulthood: The Mediating Role of Gray Matter Development Across Five Scan Waves.
Article in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Interpersonal early adversity demonstrates dissimilarity from early socioeconomic disadvantage in the course of human brain development: A meta-analysis.Neuroscience and biobehavioral reviews · 2023Pooled it
- Multisystem Environmental Factors Elucidate Shared and Distinct Associations With Brain and Behavior in Adolescents.Journal of the American Academy of Child and Adolescent Psychiatry · 2026Article
- Neighborhood socioeconomic status and adolescent brain responses to peer feedback: Testing relationships with negative and positive affect assessed outside of the lab.Development and psychopathology · 2026Article
- Psychological distress in urban Iran: a multilevel analysis of socioeconomic position and context.BMC psychology · 2026Article
- Cognitive Functioning and Its Stability Among Young Adults with Perinatal HIV Exposure or Acquisition in a U.S.-Based Longitudinal Cohort Study.AIDS and behavior · 2026Article
- Timing and tempo of puberty and neurodevelopment following adversity: A registered report.Developmental cognitive neuroscience · 2026Article
- DNA methylation in the placenta and household socioeconomic status: the SPAH study.Clinical epigenetics · 2026Article
- Individual differences in adolescent cortical development are associated with neighborhood characteristics: Longitudinal findings from the ABCD study.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Growth standards from birth to age 5: a population-specific retrospective longitudinal "WeChildren-Ningbo" study of 500 000 children and comparative analysis with WHO/national references.BMJ paediatrics open · 2026Article
- Associations of Child Amygdala Development With Borderline Personality Symptoms During Adolescence.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Income insufficiency impacts early brain development in infants facing increased psychosocial adversity: A network-based approach.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Association of Early Life Risk Factors and APOE ε4 With Incident Dementia: Evidence From 14 Years of U.S. Data.Journal of the American Geriatrics Society · 2025Article
- Associations among socioeconomic disadvantage, longitudinal changes in within-network connectivity, and academic outcomes in the ABCD study.Developmental cognitive neuroscience · 2025Article
- Hierarchical individual variation and socioeconomic impact on personalized functional network topography in children.BMC medicine · 2024Article
- Racial and ethnic socioenvironmental inequity and neuroimaging in psychiatry: a brief review of the past and recommendations for the future.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Review
- Environmental and neurodevelopmental contributors to youth mental illness.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Review
- The association of environmental factors with neurocognitive outcomes in survivors of childhood acute lymphoblastic leukemia (ALL).Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
- Childhood socioeconomic status and the pace of structural neurodevelopment: accelerated, delayed, or simply different?Trends in cognitive sciences · 2023Review
- Alcohol use and grey matter structure: Disentangling predispositional and causal contributions in human studies.Addiction biology · 2023Review
- Associations Between Socioeconomic Status, Obesity, Cognition, and White Matter Microstructure in Children.JAMA network open · 2023Article
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Authors and funding
18 authors.
Funding
Abstract
backgroundEarly low socioeconomic status (SES) is associated with poor outcomes in childhood, many of which endure into adulthood. It is critical to determine how early low SES relates to trajectories of brain development and whether these mediate relationships to poor outcomes. We use data from a unique 17-year longitudinal study with five waves of structural brain imaging to prospectively examine relationships between preschool SES and cognitive, social, academic, and psychiatric outcomes in early adulthood.
methodsChildren (n = 216, 50% female, 47.2% non-White) were recruited from a study of early onset depression and followed approximately annually. Family income-to-needs ratios (SES) were assessed when children were ages 3 to 5 years. Volumes of cortical gray and white matter and subcortical gray matter collected across five scan waves were processed using the FreeSurfer Longitudinal pipeline. When youth were ages 16+ years, cognitive function was assessed using the NIH Toolbox, and psychiatric diagnoses, high-risk behaviors, educational function, and social function were assessed using clinician administered and parent/youth report measures.
resultsLower preschool SES related to worse cognitive, high-risk, educational, and social outcomes (|standardized B| = 0.20-0.31, p values < .003). Lower SES was associated with overall lower cortical (standardized B = 0.12, p < .0001) and subcortical gray matter (standardized B = 0.17, p < .0001) volumes, as well as a shallower slope of subcortical gray matter growth over time (standardized B = 0.04, p = .012). Subcortical gray matter mediated the relationship of preschool SES to cognition and high-risk behaviors.
conclusionsThese novel longitudinal data underscore the key role of brain development in understanding the long-lasting relations of early low SES to outcomes in children.
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