ArticleProgress in neurobiology2021
Topographical and laminar distribution of audiovisual processing within human planum temporale.
Article in Progress in neurobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 23 citations in OpenAlex.
- Brain-wide fMRI responses to auditory and visual stimuli in awake mice.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Testing circuit-level theories of consciousness in humans.Trends in cognitive sciences · 2026Review
- Cross-spatial scale processing of hierarchical auditory sequences in human brains revealed using 7 T magnetic resonance imaging.Nature communications · 2025Article
- Multilayer network analysis across cortical depths in 7-T resting-state fMRI.Network neuroscience (Cambridge, Mass.) · 2025Article
- Blood nulling versus tissue suppression: Enhancing integrated VASO and perfusion (VAPER) contrast for laminar fMRI.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Article
- Multilayer Network Analysis across Cortical Depths in Resting-State 7T fMRI.bioRxiv : the preprint server for biology · 2024Article
- Neuronal Modeling of Cross-Sensory Visual Evoked Magnetoencephalography Responses in the Auditory Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Neuronal modeling of magnetoencephalography responses in auditory cortex to auditory and visual stimuli.bioRxiv : the preprint server for biology · 2024Article
- Exploring methodological frontiers in laminar fMRI.Psychoradiology · 2024Review
- Improving laminar fMRI specificity by reducing macrovascular bias revealed by respiration effects.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Unlocking near-whole-brain, layer-specific functional connectivity with 3D VAPER fMRI.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Cortical depth profiles of auditory and visual 7 T functional MRI responses in human superior temporal areas.Human brain mapping · 2023Article
- Cerebral blood volume sensitive layer-fMRI in the human auditory cortex at 7T: Challenges and capabilities.PloS one · 2023Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 4 countries.
Funding
Abstract
The brain is capable of integrating signals from multiple sensory modalities. Such multisensory integration can occur in areas that are commonly considered unisensory, such as planum temporale (PT) representing the auditory association cortex. However, the roles of different afferents (feedforward vs. feedback) to PT in multisensory processing are not well understood. Our study aims to understand that by examining laminar activity patterns in different topographical subfields of human PT under unimodal and multisensory stimuli. To this end, we adopted an advanced mesoscopic (sub-millimeter) fMRI methodology at 7 T by acquiring BOLD (blood-oxygen-level-dependent contrast, which has higher sensitivity) and VAPER (integrated blood volume and perfusion contrast, which has superior laminar specificity) signal concurrently, and performed all analyses in native fMRI space benefiting from an identical acquisition between functional and anatomical images. We found a division of function between visual and auditory processing in PT and distinct feedback mechanisms in different subareas. Specifically, anterior PT was activated more by auditory inputs and received feedback modulation in superficial layers. This feedback depended on task performance and likely arose from top-down influences from higher-order multimodal areas. In contrast, posterior PT was preferentially activated by visual inputs and received visual feedback in both superficial and deep layers, which is likely projected directly from the early visual cortex. Together, these findings provide novel insights into the mechanism of multisensory interaction in human PT at the mesoscopic spatial scale.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.