Evidence map›Paper›PMID 34273182›Full record

ArticleJournal of clinical laboratory analysis2021

Coinfection with severe acute respiratory syndrome coronavirus-2 and other respiratory viruses at a tertiary hospital in Korea.

Zehwan Kim, Jong Ho Lee

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical laboratory analysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Viral Coinfections.Viruses · 2022
    Review
  2. Coinfection between SARS-CoV-2 and other respiratory tract viruses.Journal of clinical laboratory analysis · 2022
    Article
  3. Review
  4. Treatment of Respiratory Viral Coinfections.Epidemiologia (Basel, Switzerland) · 2022
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Zehwan KimDepartment of Laboratory Medicine, Yeungnam University Medical Center, Daegu, Korea.ORCID https://orcid.org/0000-0002-4185-5270
Jong Ho LeeDepartment of Laboratory Medicine, Yeungnam University Medical Center, Daegu, Korea.ORCID https://orcid.org/0000-0002-6837-838X
Yeungnam University Medical Center · KR

Funding

Yeungnam University 2020
6 · The paper itself

Abstract

backgroundStudies have reported coinfection of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the cause of coronavirus disease-2019 (COVID-19), with other viruses that cause respiratory tract infections (RTIs). We investigated the coinfection rate of SARS-CoV-2 and other RTI-causing viruses, and whether the cycle threshold (Ct) value of a real-time reverse transcriptase PCR (RT-PCR) differed when the coinfection occurred during the first wave of COVID-19 in Daegu, Republic of Korea, in 2020.

methodsAfter performing PCR for SARS-CoV-2, we additionally tested for the presence of RTI-causing viruses to check for coinfection. Subsequently, we identified the specific coexisting respiratory viruses and calculated the coinfection rate. In addition, based on the coinfection status, we compared the Ct values obtained from RT-PCR for SARS-CoV-2 in patients who tested positive for COVID-19 PCR.

resultsOf 13,717 patients, 123 had positive results on COVID-19 PCR testing and six tested positive for an RTI-causing virus. Thus, the coinfection rate was 4.9%. There were no statistically significant differences in the mean Ct values of SARS-CoV-2 RT-PCR between coinfected and non-coinfected patients.

conclusionThis study computed the coinfection rate of SARS-CoV-2 and RTI-causing viruses and revealed that the mean Ct values in SARS-CoV-2 real-time RT-PCR did not differ according to the coinfection status.

Indexed as

AgedAged, 80 and overCoinfectionCOVID-19COVID-19 Nucleic Acid TestingFemaleHumansMaleMiddle AgedReal-Time Polymerase Chain ReactionRepublic of KoreaRespiratory Tract InfectionsSARS-CoV-2Tertiary Care CenterscoinfectionCOVID-19cycle thresholdreal-time RT-PCRSARS-CoV-2

Identifiers

PMID34273182
PMCPMC8373349
OpenAlexW3183473281

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.