Evidence map›Paper›PMID 34273167›Full record

ArticleRheumatology (Oxford, England)2022

Hospital readmission in systemic sclerosis associated pulmonary hypertension: Results from the PHAROS registry.

Kimberly Showalter, Laura C Pinheiro, Deanna Jannat-Khah, Irina Sobol, Jackie Szymonifka, Jackie Finik, Virginia D Steen, Jessica K Gordon

Open access · greenAbstract read
In one paragraph

Article in Rheumatology (Oxford, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Kimberly ShowalterDepartment of Medicine, Division of Rheumatology, Hospital for Special Surgery.ORCID 0000-0001-9343-5545
Laura C PinheiroDepartment of Medicine, Division of General Internal Medicine, Weill Cornell Medicine.
Deanna Jannat-KhahDepartment of Medicine, Division of Rheumatology, Hospital for Special Surgery.
Irina SobolDepartment of Medicine, Division of Cardiology, Weill Cornell Medicine.ORCID 0000-0002-1328-3447
Jackie SzymonifkaDepartment of Medicine, Division of Rheumatology, Hospital for Special Surgery.
Jackie FinikDepartment of Medicine, Division of Rheumatology, Hospital for Special Surgery.
Virginia D SteenDepartment of Medicine, Division of Rheumatology, MedStar Georgetown University Hospital, Washington DC, USA.
Jessica K GordonDepartment of Medicine, Division of Rheumatology, Hospital for Special Surgery.
Hospital for Special Surgery · USCornell University · USGeorgetown University · US

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
NCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1 TR002384
6 · The paper itself

Abstract

objectiveTo identify individual-level factors associated with hospital readmission among individuals with SSc-associated pulmonary hypertension (SSc-PH).

methodsIndividuals enrolled in the Pulmonary Hypertension Assessment and Recognition of Outcomes in Scleroderma (PHAROS) registry contributed clinical data related to SSc-PH disease severity and hospital admissions. Readmission was defined as a subsequent hospitalization within 12 months of any hospital discharge. Characteristics were compared between individuals with and without readmissions using Fisher's exact test, Wilcoxon rank-sum test, or Kruskal-Wallis test. Logistic regression was used to estimate associations between clinical predictors and likelihood of readmission.

resultsOf 572 individuals with SSc-PH enrolled in PHAROS, 54% had ≥1 hospitalizations between 2005 and 2016. Among individuals ever-hospitalized, 34% had ≥1 readmission. Individuals with vs without readmissions had shorter median (IQR) time between index hospitalization date and next PHAROS visit [37 (3, 80) vs 81 (42, 136) days, P <0.001]. Index admissions related to PH or SSc (vs non-PH/SSc related) were associated with an increased odds of 12-month readmission [aOR 6.6 (95% CI 3.2, 13.6) and aOR 2.2 (95% CI 1.1, 4.5), respectively]. Readmission was less likely among home oxygen users (vs non-users) (aOR 0.44; 95% CI 0.22, 0.89). Race, age, sex, disease duration and disease subtype were not associated with readmission.

conclusionThe strongest predictor for 12-month readmission was an index hospitalization reason related to PH. Home oxygen use was associated with lower odds of readmission. Future studies should determine whether testing for the need for home oxygen mediates the risk of readmission in SSc-PH.

Indexed as

Hypertension, PulmonaryScleroderma, LocalizedScleroderma, SystemicHospitalizationHumansOxygenPatient ReadmissionRegistriesRetrospective StudiesRisk FactorsOxygenhospitalizationmorbiditypulmonary hypertensionreadmissionsclerodermaSSc

Identifiers

PMID34273167
PMCPMC9216039
OpenAlexW3186891242

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.