ArticleAging2021
Association of a composite score of relative grip strength and timed up and go test with incident type 2 diabetes mellitus: Guangzhou Biobank Cohort Study.
Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 10 citations in OpenAlex.
- Associations of Sarcopenia and Sarcopenic Obesity Using Different Obesity Definitions With Memory Decline.Journal of diabetes · 2026Article
- Muscle Strength and Left Ventricular Systolic and Diastolic Dysfunction in Chronic Kidney Disease Men: A Pilot Study.Journal of clinical medicine · 2026Article
- Home-Based Transcranial Direct Current Stimulation for Menstrual Pain and Premenstrual Symptoms: A Randomized Controlled Trial.International journal of women's health · 2026Article
- Frailty and transitions across cardiometabolic disease states: evidence from multistate models in a 16-year Chinese cohort.npj aging · 2025Article
- Association between sarcopenic obesity, obesity, sarcopenia and quality of life in middle-aged and older Chinese: the Guangzhou Biobank Cohort Study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Article
- Hand Grip Strength Relative to Waist Circumference as a Means to Identify Men and Women Possessing Intact Mobility in a Cohort of Older Adults with Type 2 Diabetes.Biomedicines · 2023Article
- Association of Salt Intake with Muscle Strength and Physical Performance in Middle-Aged to Older Chinese: The Guangzhou Biobank Cohort Study.Nutrients · 2023Article
- The Associations between Upper and Lower Body Muscle Strength and Diabetes among Midlife Women.International journal of environmental research and public health · 2022Article
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Authors and funding
8 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe investigated association of a score incorporating relative grip strength (RGS) and timed up and go (TUG) test with incident type 2 diabetes mellitus (T2DM) in older Chinese.
methodsBoth RGS and TUG scores were classified into tertiles (0~2 points) and summed to yield RGS-TUG score, ranging from 0 to 4 points, with higher points indicating better physical function. Cox proportional hazards regression was used to analyze association of RGS-TUG score with incident T2DM.
results3,892 participants without T2DM were followed up for an average of 3.6 years with 240 developing T2DM. After adjustment, those with the lowest RGS-TUG score, versus the highest, had higher fasting glucose, two-hour post-load glucose and glycosylated hemoglobin A1c, with β (95% confidence interval (CI)) being 0.21 (0.08, 0.33), 1.06 (0.69, 1.43) and 0.16 (0.06, 0.27), respectively. In participants with BMI of ≥25 kg/m2, those with the lowest RGS-TUG score showed a higher risk of T2DM (adjusted hazard ratio 3.01, 95% CI 1.04-8.69). No association was found for BMI of 18.5~<25 kg/m2 (P for interaction < 0.05).
conclusionsThis is the first study showing lower RGS-TUG score was associated with increased glycemia and incident T2DM in older people with overweight/obesity. The underlying mechanisms warrant further investigation.
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