ArticleStress and health : journal of the International Society for the Investigation of Stress2022
Impact of the COVID-19 pandemic on inflammatory bowel disease: The role of emotional stress and social isolation.
Article in Stress and health : journal of the International Society for the Investigation of Stress, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 31 citations in OpenAlex.
- Experiences and perceptions of IBD-related psychological distress in persons living with IBD.Journal of the Canadian Association of Gastroenterology · 2026Article
- Impact of Social Isolation on Inflammatory Bowel Disease Risk and the Mitigating Effect of a Healthy Lifestyle.International journal of behavioral medicine · 2026Article
- Lonely minds, inflamed guts: metabolic and circulating protein pathways linking social isolation and loneliness to inflammatory bowel disease.Translational psychiatry · 2026Article
- Exploring Inflammatory Bowel Disease Discourse on Reddit Throughout the COVID-19 Pandemic Using OpenAI's GPT-3.5 Turbo Model: Classification Model Validation and Case Study.Journal of medical Internet research · 2025Article
- The Relationship Between Loneliness, Social Isolation, and Inflammatory Bowel Disease: A Narrative Review.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2024Review
- The impact of the COVID-19 surge after the end of China's Zero-COVID policy on the health-related quality of life of IBD patients.BMC gastroenterology · 2024Article
- Racial and Ethnic Disparities in Patients With Inflammatory Bowel Disease: An Online Survey.Inflammatory bowel diseases · 2024Article
- Perceptions of and Experiences with the COVID-19 Pandemic Among Individuals with Inflammatory Bowel Disease.Journal of clinical psychology in medical settings · 2024Article
- Four-year follow-up of psychiatric and psychosomatic profile in patients with Inflammatory Bowel Disease (IBD).BMC psychology · 2024Article
- Life changes, self-prevention, knowledge and mental health among inflammatory bowel disease patients during COVID-19 pandemic: a cross-sectional study.Frontiers in public health · 2024Article
- The Impact of COVID-19 on Health Anxiety and Perceived Stress Among Persons with IBD: A Population-representative Study.Journal of the Canadian Association of Gastroenterology · 2023Article
- Article
- Impact of COVID-19 Pandemic on the Quality of Life of IBD Patients.Medicina (Kaunas, Lithuania) · 2022Observational
- Impact of the COVID-19 pandemic on inflammatory bowel disease: The role of emotional stress and social isolation.Stress and health : journal of the International Society for the Investigation of Stress · 2022Article
- Cognitive, emotional, physical, and behavioral stress-related symptoms and coping strategies among university students during the third wave of COVID-19 pandemic.Frontiers in psychiatry · 2022Article
- Associations between inflammatory bowel disease, social isolation, and mortality: evidence from a longitudinal cohort study.Therapeutic advances in gastroenterology · 2022Article
- Impact of the SARS-CoV-2 Delta Variant on the Psychological States and Health-Related Quality of Life in Patients With Crohn's Disease.Frontiers in medicine · 2022Article
- Patient Engagement in Health Management as a Mediator Between Perceived Risk and COVID-19 Related Distress in Patients With IBD: A Structural Equation Model.Frontiers in psychiatry · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inflammatory bowel disease (IBD) is a chronic health condition exacerbated by negative emotional stress experiences. In the current study, we examined whether the outbreak of the COVID-19 pandemic coincided with an increase in stress experiences and accordingly an aggravation of disease activity in IBD patients. Sixty-three IBD patients (30 Crohn's disease or CD, 33 ulcerative colitis) completed an online survey during the COVID-19-related lockdown, assessing clinical disease activity, disease-related quality of life, presence of functional gastrointestinal symptoms, social isolation and stress experiences. Scores were then compared to pre-lockdown baseline screening. The pandemic yielded a significant baseline-to-lockdown increase in emotional stress and social isolation. Stress increments, particularly those occasioned by interpersonal tension and excessive interpersonal proximity, were associated with a worsening of functional gastrointestinal symptoms. Exacerbations of loneliness coincided with an escalation of CD activity, functional gastrointestinal symptoms and a decline in subjective health. Lastly, COVID-19 anxiety was significantly related to CD symptom severity and social dysfunction. The findings show that shifts in IBD expression are closely linked to changes in emotional stress experiences and interpersonal relatedness. As such, they contribute to a better understanding of inter-individual differences in IBD progression and provide leads for therapeutic interventions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.