Evidence map›Paper›PMID 34273003›Full record

ReviewMedical oncology (Northwood, London, England)2021

Resveratrol effects in oral cancer cells: a comprehensive review.

Tamires Cunha Almeida, Glenda Nicioli da Silva, Daniel Vitor de Souza, Andrea Cristina de Moraes Malinverni, Odair Aguiar, Debora Estadella, Daniel Araki Ribeiro

Abstract readReview
PubMed Publisher
In one paragraph

Review in Medical oncology (Northwood, London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tamires Cunha AlmeidaLaboratory of Clinical Research, Federal University of Ouro Preto, Ouro Preto, MG, Brazil.
Glenda Nicioli da SilvaLaboratory of Clinical Research, Federal University of Ouro Preto, Ouro Preto, MG, Brazil.
Daniel Vitor de SouzaDepartment of Biosciences, Institute of Health and Society, Federal University of São Paulo, Rua Silva Jardim, UNIFESP, 136, Room 332, Vila Mathias, Santos, SP, 11050-020, Brazil.
Andrea Cristina de Moraes MalinverniDepartment of Pathology, Paulista Medical School, Federal University of São Paulo, UNIFESP, Sao Paulo, SP, Brazil.
Odair AguiarDepartment of Biosciences, Institute of Health and Society, Federal University of São Paulo, Rua Silva Jardim, UNIFESP, 136, Room 332, Vila Mathias, Santos, SP, 11050-020, Brazil.
Debora EstadellaDepartment of Biosciences, Institute of Health and Society, Federal University of São Paulo, Rua Silva Jardim, UNIFESP, 136, Room 332, Vila Mathias, Santos, SP, 11050-020, Brazil.
Daniel Araki RibeiroDepartment of Biosciences, Institute of Health and Society, Federal University of São Paulo, Rua Silva Jardim, UNIFESP, 136, Room 332, Vila Mathias, Santos, SP, 11050-020, Brazil. daribeiro@unifesp.br.ORCID http://orcid.org/0000-0001-5057-4983

Funding

capes 001cnpq 001
6 · The paper itself

Abstract

Oral cancer is a very common tumor worldwide with high incidence and mortality. The treatment of oral cancer involves surgery, radio- and chemotherapy; however, high failure rates and toxicity are noticed. Thus, the search of new drugs aiming a more effective treatment is welcomed. Natural products present chemopreventive and anti-cancer effects. Resveratrol is a naturally occurring antioxidant that contains several health benefits, including anti-inflammatory and antiproliferative activities. This review discusses the different action mechanisms of resveratrol related in the in vitro and in vivo studies using models of oral cancer.

Indexed as

Antineoplastic Agents, PhytogenicAntioxidantsCell SurvivalHumansMouth NeoplasmsOxidative StressResveratrolAntineoplastic Agents, PhytogenicAntioxidantsResveratrolIn vitroIn vivoOral cancerResveratrol

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.