Evidence map›Paper›PMID 34272976›Full record

ArticleEuropean archives of psychiatry and clinical neuroscience2022

Characterizing the features and course of psychiatric symptoms in children and adolescents with autoimmune encephalitis.

R Rosello, B Girela-Serrano, S Gómez, B Baig, M Lim, S Taylor

Open access · hybridAbstract read
In one paragraph

Article in European archives of psychiatry and clinical neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Early psychiatric manifestations in pediatric autoimmune encephalitis: clinical data from a tertiary center.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Observational
  3. Article
  4. Article
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

R Rosello *Division of Psychiatry, Imperial College, London, UK.
B Girela-Serrano *Division of Psychiatry, Imperial College, London, UK.
S GómezDivision of Psychiatry, King's College, London, UK.
B BaigSouth London and Maudsley NHS Trust, London, UK.
M Lim *Children's Neurosciences Centre, Evelina London Children's Hospital, London, UK. Ming.lim@gstt.nhs.uk.ORCID http://orcid.org/0000-0001-7738-8910
S Taylor *Division of Psychiatry, Imperial College, London, UK.
Imperial College London · GBKing's College London · GBSouth London and Maudsley NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune encephalitis (AE) can present like a psychiatric disorder. We aimed to illustrate the psychiatric manifestations, course and management of AE in a paediatric cohort. Neuropsychiatric symptoms, investigations and treatment were retrospectively retrieved in 16 patients (mean age 11.31, SD 2.98) with an AE diagnosis at the liaison psychiatry services in two UK tertiary paediatric centres. Psychiatric presentation was characterised by an acute polysymptomatic (predominantly agitation, anger outbursts/aggressiveness, hallucinations, and emotional lability) onset. Antipsychotics produced side effects and significant worsening of symptoms in four cases, and benzodiazepines were commonly used. This psychiatric phenotype should make clinicians suspect the diagnosis of AE and carefully consider use of treatments.

Indexed as

Anti-N-Methyl-D-Aspartate Receptor EncephalitisHashimoto DiseaseMental DisordersAdolescentChildHallucinationsHumansRetrospective StudiesAnti-N-methyl-D-aspartate receptor encephalitisEncephalitisPaediatricsPsychiatryPsychopharmacology

Identifiers

PMID34272976
PMCPMC8938365
OpenAlexW3182284637

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.